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Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Fig. 8.2 Frameshift Mutation As a Result of Base Addition.

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Presentation on theme: "Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Fig. 8.2 Frameshift Mutation As a Result of Base Addition."— Presentation transcript:

1 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Fig. 8.2 Frameshift Mutation As a Result of Base Addition Slide number 1 A Translation G C CG A T GC C A AU T T T C mRNADNA Wild type Amino acid Direction of transcription and translation 5' 3' G C C A T G C C A AU T T T mRNADNA Mutant Amino acid 5'3'5'3' 5'3'5' Frameshift G C U G U A A A G Nucleotide added-C A Arg Tyr Val Lys Arg Tyr Gly Chain termination U G A A A U G G C G C

2 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Fig. 8.2 Frameshift Mutation As a Result of Base Addition Slide number 2 Translation G C CG A TA GC C A AU T T T C mRNADNA Amino acid Direction of transcription and translation 5' 3' 5'3' 5' G C U G U A A A G Arg Tyr Val Lys Wild type

3 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Fig. 8.2 Frameshift Mutation As a Result of Base Addition Slide number 3 Translation G C CG A TA GC C A AU T T T C mRNADNA Amino acid Direction of transcription and translation 5' 3' G C C A T G C C A A T T T DNA 5'3'5' 3'5'3' G C U G U A A A G Arg Tyr Val Lys Frameshift Wild typeMutant Nucleotide added-C

4 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Fig. 8.2 Frameshift Mutation As a Result of Base Addition Slide number 4 Translation G C CG A TA GC C A AU T T T C mRNADNA Amino acid Direction of transcription and translation 5' 3' G C C A T G C C A AU T T T mRNADNA 5'3'5'3' 5'3'5' G C U G U A A A G A Arg Tyr Val Lys U G A A A U G G C G C Frameshift Wild typeMutant Nucleotide added-C

5 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Fig. 8.2 Frameshift Mutation As a Result of Base Addition Slide number 5 Translation G C CG A TA GC C A AU T T T C mRNADNA Amino acid Direction of transcription and translation 5' 3' G C C A T G C C A AU T T T mRNADNA Amino acid 5'3'5'3' 5'3'5' G C U G U A A A G Nucleotide added-C A Arg Tyr Val Lys Arg Tyr Gly Chain termination U G A A A U G G C G C Frameshift Wild typeMutant

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