1. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Osteopathic EPEC Osteopathic EPEC Education for Osteopathic Physicians on End-of-Life Care Based on The EPEC Project, created by the American Medical Association and supported by the Robert Wood Johnson Foundation. Adapted by the American Osteopathic Association for educational use. American Osteopathic Association AOA: Treating Our Family and Yours

2. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Module 11 Withholding, Withdrawing Treatment

3. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Objectives Know the principles for withholding or withdrawing therapy Apply these principles to the withholding or withdrawal of Artificial feeding, hydration Ventilation Cardiopulmonary resuscitation

4. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Role of the physician... The physician helps the patient and family Elucidate their own values Decide about life-sustaining treatments Dispel misconceptions Understand goals of care Facilitate decisions, reassess regularly

5. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours... Role of the physician Discuss alternatives Including palliative and hospice care Document preferences, medical orders Involve, inform other team members Assure comfort, non-abandonment

6. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Common concerns... Legally required to “do everything?” Is withdrawal, withholding euthanasia? Are you killing the patient when you remove a ventilator or treat pain?

7. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours... Common concerns Can the treatment of symptoms constitute euthanasia? Is the use of substantial doses of opioids euthanasia?

8. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Life-sustaining treatments Resuscitation Elective intubation Surgery Dialysis Blood transfusions, blood products Diagnostic tests Artificial nutrition, hydration Antibiotics Other treatments Future hospital, ICU admissions

9. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours 8-step protocol to discuss treatment preferences... 1.Be familiar with policies, statutes 2.Appropriate setting for the discussion 3.Ask the patient, family what they understand 4.Discuss general goals of care

10. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours... 8-step protocol to discuss treatment preferences 5.Establish context for the discussion 6.Discuss specific treatment preferences 7.Respond to emotions 8.Establish and implement the plan

11. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Aspects of informed consent Problem treatment would address What is involved in the treatment / procedure What is likely to happen if the patient decides not to have the treatment Treatment benefits Treatment burdens

12. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Example 1: Artifical nutrition, hydration Difficult to discuss Food, water are symbols of caring

13. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Review goals of care Establish overall goals of care Will artificial feeding, hydration help achieve these goals?

14. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Address misperceptions Cause of poor appetite, fatigue Relief of dry mouth Delirium Urine output

15. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Help family with need to give care Identify feelings, emotional needs Identify other ways to demonstrate caring Teach the skills they need

16. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Normal dying Loss of appetite Decreased oral fluid intake Artificial food / fluids may make situation worse Breathlessness Edema Ascites Nausea / vomiting

17. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Example 2: Ventilator withdrawal Rare, challenging Ask for assistance Assess appropriateness of request Role in achieving overall goals of care

18. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Immediate extubation Remove the endotracheal tube after appropriate suctioning Give humidified air or oxygen to prevent the airway from drying Ethically sound practice

19. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Terminal weaning Rate, PEEP, oxygen levels are decreased first Over 30–60 minutes or longer A Briggs T piece may be used in place of the ventilator Patients may then be extubated

20. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Ensure patient comfort Anticipate and prevent discomfort, offer OMT when indicated Have anxiolytics, opioids immediately available Titrate rapidly to comfort Be present to assess, reevaluate

21. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Prevent symptoms Breathlessness Opioids Anxiety Benzodiazepines

22. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Preparing for ventilator withdrawal Determine degree of desired consciousness Bolus 2-20 mg morphine IV, then continuous infusion Bolus 1-2 mg midazolam IV, then continuous infusion Titrate to degree of consciousness, comfort

23. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Prepare the family... Describe the procedure Reassure that comfort is a primary concern Medication is available Patient may need to sleep to be comfortable

24. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours... Prepare the family Involuntary movements Provide love and support Describe uncertainty

25. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Prior to withdrawal Prior to procedure Discussion and agreement to discontinue ­with patient (if conscious) ­with family, nurses, respiratory therapists Document on the patient’s chart

26. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Withdrawal Protocol -– Part 1 Procedure Shut off alarms Remove restraints NG tube is removed Family is invited into the room Pressors are turned off Parents may hold child

27. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Withdrawal protocol -- Part 2 Establish adequate symptom control prior to extubation Have medications IN HAND Midazolam, lorazepam, or diazepam Set FiO 2 to 21% Adjust medications Remove the ET tube

28. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Withdrawal Protocol -- Part 3... Invite family to bedside Washcloth, oral suction catheter, facial tissues Reassess frequently

29. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours... Withdrawal Protocol – Part 3 After the patient dies Talk with family and staff Provide acute grief support Offer bereavement support to family members Follow up to ensure they are okay

30. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Example 3: Cardiopulmonary resuscitation Establish general goals of care Use understandable language Avoid implying the impossible Ask about other life-prolonging therapies Affirm what you will be doing Clarify that resuscitation really means an attempt with no guarantee of success

31. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Write appropriate medical orders DNR DNI Do not transfer Others POLST

32. EPECEPECEPECEPEC American Osteopathic Association AOA: Treating our Family and Yours Withholding, Withdrawing Treatment Summary