1. Septic Implantation Syndrome Analysis of 29 canine and 11 feline cases Dick Dubielzig and Chris Pirie Comparative Ocular Pathology Laboratory University of Madison-Wisconsin

8. Canine Cases 29 cases of 9, 300 ocular submissions 10 documented cases of cat scratch Typical ophthalmic findings included –chronic, poorly responsive anterior uveitis –cataract formation –+/- anterior or posterior synechiae, corneal scar, and/or glaucoma

9. Canine Cases Signalment –Breed No predilection, however, small breeds and young (<1 year) large breed dogs over represented –Gender 3 F, 10 FS, 3 M, 12 MC, 1 unknown –Age Mean 7.4 years (range 3.5 months to 15 years)

10. Canine Cases Globe involvement –15 OD vs 14 OS History –10 cat scratch vs 19 unknown or suspected Duration (2 unknown) Known CatUnknownTotal < 1 week314 1 week- 1 month11112 1-4 months538 >4 months123

11. Canine Cases Intra-lenticular bacteria –7 negative of H+E and gram stain –22 positive for bacteria 19 gram positive cocci 2 gram positive rods 1 gram positive cocci and rods

12. Feline Cases 11 cases out of 3, 400 ocular submissions 2 documented, 9 unknown or suspected cases Signalment –Breed 8 DSH, 1 DMH, 1 DLH, 1 Persian –Gender 5 FS, 1 M, 5 MC –Age Mean 5.3 years (range 1year to 14 years)

13. Feline Cases Duration (2 unknown) Intra-lenticular bacteria –4 negative of H+E and gram stain –4 gram positive cocci –1 Candida –1 gram positive and negative bacilli –1 gram positive cocci, gram positive and negative bacilli Known Cat Scratch UnknownTotal < 1 week000 1 week- 1month235 1-4 months044

15. What about phacoclastic inflammaton? Phacoclastic uveitis is a term used to characterize the inflammation seen around a ruptured lens as is seen in these cases. The term carries with it the implication that the inflammation is caused by the release of lens proteins otherwise sequestered. I believe that in these dogs the inflammation is do to bacterial infection and not simply exposure of lens proteins.