1. EX. 20 Antibiotic Disk Sensitivity

2. Antibiotics
Naturally occurring compounds produced by bacteria and or fungi, that kill or inhibit other microbes
Many Antibiotics are produced by
2 Genera of Bacteria
Streptomyces
Bacillus
1 Fungal Genus
Penicillium

3. Common Antibiotics Stretomycin – Streptomyces Bacitracin - Bacillus
Penicillin Penicillium
Protein synthesis
70S Ribosme
Cell Wall synthesis

4. Selective toxicity
The antibiotic must harm the pathogen without harming the host cell
Antibiotics do this by:
1. Attacking the 70S Ribosome (Protein synthesis)
2. Attacking the Cell Wall

5. Kirby-Bauer Antibiotic Disk Sensitivity Test

6. Kirby-Bauer Antibiotic Disk Sensitivity Test

7. MIC Minimum Inhibitory Concentration
Least amount of an antibiotic that will inhibit the growth of a microbe

8. MRSA Vancomycin VRE Methicillin Resistant Staphylococcus aureus
Last line of defense against MRSA – which has led to
VRE
Vancomycin Resistant Enterococci