2. Technology Advances Mark Fornalik & Brian Aylward

3. Technical Prowess & Innovation Our historical success has been based on the design and manufacture of precision, multi-layered films consisting of high-performance, engineered materials with unique physical and chemical properties Small Particle Manufacturing

4. Ag Antimicrobials Technology Effectiveness of any Ag AM will depend on three factors: 1. Ag form (solubility, chemistry, size, etc.) 2. Delivery vehicle (polymer permeability, Ag release rate, surface properties, etc.) 3. Microbial environment (water content, pH, ionic nature/strength, viscosity, flow, etc.) Knowledge of all three factors is needed to design effective products

5. P Ribosom PM Protein SH NH2 Gram Negative Bacteria P O L P CM DNA RNA Gram Positive Bacteria P TA O MycobacteriaA M Yeast G O MP.G.C. TA Ag + /Cell Interaction Most biocides only impact one cellular function Most biocides only impact one cellular function Silver can disrupt cell growth by multiple means Silver can disrupt cell growth by multiple means

6. P Ribosom PM Protein SH NH2 Gram Negative Bacteria P O L P CM DNA RNA Gram Positive Bacteria P TA O MycobacteriaA M Yeast G O MP.G.C. TA Ag + /Cell Interaction Most biocides only impact one cellular function Most biocides only impact one cellular function Silver can disrupt cell growth by multiple means Silver can disrupt cell growth by multiple means  Modification of Plasma Membrane

7. P Ribosom PM Protein SH NH2 Gram Negative Bacteria P O L P CM DNA RNA Gram Positive Bacteria P TA O MycobacteriaA M Yeast G O MP.G.C. TA Ag + /Cell Interaction Most biocides only impact one cellular function Most biocides only impact one cellular function Silver can disrupt cell growth by multiple means Silver can disrupt cell growth by multiple means  Interferes with DNA and RNA functionality

8. P Ribosom PM Protein SH NH2 Gram Negative Bacteria P O L P CM DNA RNA Gram Positive Bacteria P TA O MycobacteriaA M Yeast G O MP.G.C. TA Ag + /Cell Interaction Most biocides only impact one cellular function Most biocides only impact one cellular function Silver can disrupt cell growth by multiple means Silver can disrupt cell growth by multiple means  Blocking of Thiol groups on proteins and enzymes

9. Biocides, Biostats & Biofilms Killing Microbes Ag + biostatic Stopping Biogrowth planktonic Ag + biocidal Ag +

10. Time Antimicrobial Contamination (colony forming units) Surface Concentration of Microbial Species With Time Time Surface concentration of silver species Surface Concentration of Silver Species With Time Time Antimicrobial Contamination (colony forming units) Surface Concentration of Microbial Species With Time Time Surface concentration of silver species Surface Concentration of Silver Species With Time Silpure Ag-Antimicrobial Old Generation Ag-Antimicrobial

11. Silpure Formulation ActiveActive –Specially formulated silver chemistry for controlled ion release in microbial environment (textiles) –Manufactured to specific particle size, shape and morphology for optimal surface coverage and antimicrobial efficacy

12. Silpure Formulation… Binder SystemBinder System –Polymeric binder system to provide adhesion of silver to fabric materials –Co developed with silver technology to provide additional control of ion release for long lasting antimicrobial efficacy –Designed for optimal performance in padding processes –Compatible with a wide range of textile auxiliaries

13. Untreated Fabric- A Closer Look

14. Treated Fabric  Topically adhered  Uniform Coverage  Maximum Durability

15.  Target application will be 1-3% (performance dependent)  Active (silver) concentration in blended product will be 0.24%  Final goods will therefore contain between 0.0024 and 0.0072% active (24-72 ppm) Product Information

16. Silpure FBR-5 Performance Evaluation Eliminates bacteria growth Highly durable antimicrobial performance