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DNA POLIMERASE By: Muhartri Sanjaya 20512046 Nishia W Meray 20511034.

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Presentation on theme: "DNA POLIMERASE By: Muhartri Sanjaya 20512046 Nishia W Meray 20511034."— Presentation transcript:

1 DNA POLIMERASE By: Muhartri Sanjaya Nishia W Meray

2 reaksi polimerisasi deoksiribonukleotida
DNA POLIMERASE Replikasi DNA Reparasi DNA reaksi polimerisasi deoksiribonukleotida Rantai DNA

3 Tatanama DNA Transferase EC Kelas Transferase Gugus fosfat

4 Klasifikasi E. Coli Pol I (Kelas A) E. Coli Pol II (Kelas B)
E. Coli Pol III (Kelas C) Euryarchaeotic Pol II (Kelas D) Pol β Manusia (Kelas X) E. Coli UmuC/DinB (Kelas Y)

5 Peran DNA Polimerase Elongasi Proofreading
Pemanjangan rantai nukleotida Mengenali kekeliruan dan memperbaiki

6 Struktur DNA Polimerase
Tumb Finger Palm

7 Mekanisme Kerja

8 Residu Katalitik & Efektor
Efektor yang mengandung ion logam Residu Katalitik aspartat 705 dan 882

9 Aplikasi dan Modifikasi
DNA Pol I PCR E. Coli Thermus Aquaticus Bukan Termofilik

10

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