1. Figure 1. Number of Tuberculosis Cases: California, 1930-2011 California Department of Public Health, Tuberculosis Control Branch Number of Tuberculosis Cases Year

2. Figure 2. Number of Tuberculosis Cases and Case Rates: California, 2002-2011 * Case Rate per 100,000 Number of Cases Case Rate per 100,000 Population National Case Rate California Department of Public Health, Tuberculosis Control Branch * Number of Cases

3. Figure 3. Tuberculosis Cases by Race/Ethnicity: California, 2011 Asian/Pacific Islander 1,137 (48.9%) Hispanic 848 (36.5%) Unknown 1 (<0.1%) Black 137 (5.9%) American Indian/ Alaska Native 5 (0.2%) White 197 (8.5%) California Department of Public Health, Tuberculosis Control Branch 76

4. Figure 4. Tuberculosis Case Rates by Race/Ethnicity: California, 2002-2011 Cases per 100,000 California Department of Public Health, Tuberculosis Control Branch

5. Figure 5. Tuberculosis Cases in Foreign-born and U.S.-born Persons: California, 2002-2011 Number of Cases Percent of Cases California Department of Public Health, Tuberculosis Control Branch 78

6. Figure 6. Tuberculosis Cases by Country of Origin: California, 2011 U.S.-born 511 (21.9%) Foreign-born 1,787 (76.9%) Unknown 27 (1.2%) Philippines 375 (21.0%) Mexico 497 (27.8%) All Other Countries 675 (37.8%) Vietnam 240 (13.4%) California Department of Public Health, Tuberculosis Control Branch

7. Figure 7. Tuberculosis Cases in Persons 0-4 Years of Age: California, 2002-2011 Number of Cases Percent of Cases Number of Cases Percent of Cases California Department of Public Health, Tuberculosis Control Branch Year 2002200320042005 200620072008200920102011

8. Figure 8. Tuberculosis Cases by Verification Criteria: California, 2011 Provider Diagnosis 98 (4.2%) Positive Culture 1,840 (79.1%) Clinical Case 336 (14.5%) Positive Smear 12 (0.5%) California Department of Public Health, Tuberculosis Control Branch 81 NAAT* 39 (1.7%) *NAAT= Nucleic Acid Amplification Test

9. Figure 9. Deaths in Persons with Tuberculosis: California, 2000-2009 Percent of Cases Number of Deaths California Department of Public Health, Tuberculosis Control Branch Dead at Diagnosis Died During Treatment Died Before Starting Treatment Percent Dying with Tuberculosis

10. Figure 10. Tuberculosis Cases by HIV/AIDS Diagnosis:* California, 2001-2010 Number of Cases with HIV/AIDS Percent of Cases with HIV/AIDS * Match found in HIV/AIDS Registry, California Department of Public Health, Office of AIDS Number of Tuberculosis Cases with HIV/AIDS Percent of Tuberculosis Cases with HIV/AIDS 83 California Department of Public Health, Tuberculosis Control Branch

11. Figure 11. HIV/AIDS-associated Tuberculosis* by Race/Ethnicity: California, 2001-2010 Number of Cases with HIV/AIDS * Match found in HIV/AIDS Registry, California Department of Public Health, Office of AIDS California Department of Public Health, Tuberculosis Control Branch

12. Figure 12. Tuberculosis Cases with Multidrug Resistance (MDR) on Initial or Final Drug Susceptibility Testing:* California, 2000-2009 Number of MDR Tuberculosis Cases *Cases with resistance to at least isoniazid, and either rifampin, rifabutin or rifapentine reported on the Initial Drug Susceptibility Report (Follow-up 1) or on the Case Completion Report (Follow-up 2) 35 43 34 41 36 37 28 32 33 38 2001 200920002002200320042005200620072008 California Department of Public Health, Tuberculosis Control Branch Initial Susceptibility TestFinal Susceptibility Test

13. Figure 13. Tuberculosis Cases with Initial Multidrug Resistance (MDR):* California, 2007-2011 *Cases with initial drug resistance to at least isoniazid, and either rifampin, rifabutin or rifapentine California Department of Public Health, Tuberculosis Control Branch Long Beach Pasadena Berkeley San Francisco  25 cases 15-24 cases 5-14 cases 1-4 cases None Initial MDR Cases: 2007-2011

14. Figure 14. Tuberculosis Cases 1 by Outcome of Therapy: California, 2009 Completed Therapy  12 Months 1,780 (74.5%) Completed Therapy >12 Months 235 (9.8%) Moved 2 97 (4.1%) Died 180 (7.5%) Lost 3 21 (0.9%) Refused 17 (0.7%) Other 31 (1.3%) 1 Patient was alive at diagnosis and started on an initial drug regimen of two or more drugs. 2 Patient moved to another jurisdiction with a known forwarding address before treatment was completed; final outcome not available. 3 Patient could not be located prior to the completion of treatment. No Information 28 (1.2%) California Department of Public Health, Tuberculosis Control Branch

15. Figure 15. Outcome in Tuberculosis Cases for Whom One Year or Less of Treatment was Indicated 1 : California, 2009 Completed Therapy  12 Months 1,770 (76.2%) Completed Therapy >12 Months 195 (8.4%) Moved 2 91 (3.9%) Died 175 (7.5%) Lost 3 21 (0.9%) Refused 16 (0.7%) Other 29 (1.2%) No Information 25 (1.1%) 1 Excludes cases with rifampin resistant disease, cases with meningeal disease, and cases less than 15 years of age with disseminated tuberculosis disease. 2 Patient moved to another jurisdiction with a known forwarding address before treatment was completed; final outcome not available. 3 Patient could not be located prior to the completion of treatment. California Department of Public Health, Tuberculosis Control Branch

16. Figure 16. Outcome in Tuberculosis Cases for Whom Greater than One Year of Treatment was Indicated: 1 California, 2009 Completed Therapy  12 Months 10 (14.9%) Completed Therapy >12 Months 40 (60.0%) Moved 2 6 (9.0%) Died 5 (7.5%) No Information 3 (4.5%) 1 Includes cases with rifampin resistant disease, cases with meningeal disease, and cases less than 15 years of age with disseminated tuberculosis disease. 2 Patient moved to another jurisdiction with a known forwarding address before treatment was completed; final outcome not available. California Department of Public Health, Tuberculosis Control Branch Refused 1 (2.0%) Other 2 (3.0%)

17. Figure 17. Completion of Tuberculosis Therapy: California, 2000-2009 Completed Completed in 1 year or less Note: Excludes cases with rifampin resistant disease, cases with meningeal disease, cases less than 15 years of age with disseminated tuberculosis disease, and those that died during treatment. 90 California Department of Public Health, Tuberculosis Control Branch