1. Gene expression Chapter 15 Genes and Development

7. Central dogma 1956 version of Central dogma by Francis Crick

8. Central dogma 1958 version of Central dogma

12. Genetic code

15. Transcription

19. DNA P’ase

21. RNA polymerase-3D at Online Macromolecular Museum

23. Transcription

28. RNA polymerase-3D at Online Macromolecular Museum

32. Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. E1I1E2I2E3I3E4I4 Transcription Introns are removed Exons Introns Mature mRNA 3’ poly-A tail5’ cap 3’ poly-A tail Primary RNA transcript DNA template

33. Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. E1I1E 2I 2E3I3E 4I 4 Transcription Introns are removed Intron Exon DNA 1 2 3 4 5 6 7 a. b.c. Exons Introns mRNA Mature mRNA 3׳ poly-A tail 5׳ cap 3׳ poly-A tail Primary RNA transcript DNA template b: Courtesy of Dr. Bert O’Malley, Baylor College of Medicine

35. Translation

48. Genetic code