1. Bio Domain Broker integration with ECA Engine r3 Annual Meeting 2007 Working Group I5 Tiago Franco – FCT/UNL München, 28th of February 2007

2. March 22nd, 2006I5: Evolution and Reactivity2 Objectives Demonstrate a Use Case Scenario for the ECA engine r3 Introduce a domain Broker for Bio- Informatics

3. March 22nd, 2006I5: Evolution and Reactivity3 General Overview Domain Broker for Bio-Informatics (B- Domain) Detects the publication of new Proteins (PDB) Performs the match of a given criterion to the newly published Structures Implements a language that exposes computational services to be executed over a given structure r3 ECA Engine Exposes Event, Condition, Action functionalities Is notified when a new Structure is published Delegates the verification of the mathing criteria to B-Domain If a criterion matches the engine stores the result in the B-Domain

4. March 22nd, 2006I5: Evolution and Reactivity4 User Interaction

5. March 22nd, 2006I5: Evolution and Reactivity5 User Interaction

6. March 22nd, 2006I5: Evolution and Reactivity6 Future Work Domain Broker for Bio-Informatics (B- Domain) Integrate a Bio-Informatics ontology into the B- Domain Language Add support for condition matching using UniPort & PubMed Support logical operators (And, Or) for condition matching ECA Framework and r3 See I5 presentation tomorrow

7. March 22nd, 2006I5: Evolution and Reactivity7 Comments & Questions? Thank you.