Presentation is loading. Please wait.

Presentation is loading. Please wait.

M0120 series (α-mCD86) Binding Assessment on ELISA; M0115 series (α-hCD86) Binding Assessment on ELISA; Mono IL10 series binding assessment on ELISA In-vitro.

Published byKendrick Kane Modified over 10 years ago

Similar presentations

Presentation on theme: "M0120 series (α-mCD86) Binding Assessment on ELISA; M0115 series (α-hCD86) Binding Assessment on ELISA; Mono IL10 series binding assessment on ELISA In-vitro."— Presentation transcript:

1 M0120 series (α-mCD86) Binding Assessment on ELISA; M0115 series (α-hCD86) Binding Assessment on ELISA; Mono IL10 series binding assessment on ELISA In-vitro efficacy evaluation of α-hCD86 end of X-2: IDO activation; In-vitro efficacy evaluation of IL10 end of X-2: pSTAT3 activation;

2 Assessment of M0120 Binding towards mCD86 by ELISA mCD86-AFH Xceptor-2 Anti- hFc-HRP mCD86-AFH Xceptor-2 Anti- hIL10-HRP

3 Assessment of M0120 X2 Binding towards IL10Ra by ELISA hIL10Ra Xceptor-2 Anti- hFc-HRP

4 Assessment of M0120 X2 Binding towards mCD86 on A20 Cell Line Xceptor-2 Anti- hFc-PE A20 CD86

5 Assessment of M0115 X2 Binding towards mCD86 by ELISA hCD86-mIg Xceptor-2 Anti- hFc-HRP

6 Assessment of M0115 X2 Binding towards IL10Ra by ELISA hIL10Ra Xceptor-2 Anti- hFc-HRP

7 pSTAT3 activation Cell line Selection – WIL2S has few IL10R expressed: – HUVEC cell line: Eur J Immunol. 2007 Jan;37(1):177-92. – MC/9 cell line: Good proliferation inhibition by X2. Intracellular staining 1.08% No stain CD19 IL10R

8 IDO activation Cell line Selection: WIL2S Intracellular Staining: – Santa Cruse mAb – Epitomic poly-Ab Time course: 30 min => 24 hour

Download ppt "M0120 series (α-mCD86) Binding Assessment on ELISA; M0115 series (α-hCD86) Binding Assessment on ELISA; Mono IL10 series binding assessment on ELISA In-vitro."

Similar presentations

Evaluate the expression for the given value 1.9 b+7 when b=14 A. 189 B. 63 C. 18 D. 133.

Evaluate the expression for the given value 1.9 b+7 when b=14 A. 189 B. 63 C. 18 D. 133.
Vascular Endothelial Growth Factor and Basic Fibroblast Growth Factor Induce Expression of CXCR4 on Human Endothelial Cells  Rosalba Salcedo, Ken Wasserman,

Vascular Endothelial Growth Factor and Basic Fibroblast Growth Factor Induce Expression of CXCR4 on Human Endothelial Cells  Rosalba Salcedo, Ken Wasserman,
Figure 6. The effect of GV1001 on ENO1-induced pro-inflammatory cytokine production in RA PBMCs. RA PBMCs were pre-treated with GV1001 (100 µM) for 1 h.

Figure 6. The effect of GV1001 on ENO1-induced pro-inflammatory cytokine production in RA PBMCs. RA PBMCs were pre-treated with GV1001 (100 µM) for 1 h.
Figure 1 Protective effects of acellular pertussis vaccines (A–F) in the respiratory infection model. Mice were challenged by exposure to an aerosol of.

Figure 1 Protective effects of acellular pertussis vaccines (A–F) in the respiratory infection model. Mice were challenged by exposure to an aerosol of.
Fig. 1. Time course of total cells, protein concentration and cytokines in BAL fluid after LPS challenge. The number of total cells, neutrophils and macrophages.

Fig. 1. Time course of total cells, protein concentration and cytokines in BAL fluid after LPS challenge. The number of total cells, neutrophils and macrophages.
NK cells inhibited the expansion and function of ILC2s in vitro via IFN-γ. NK cells inhibited the expansion and function of ILC2s in vitro via IFN-γ. ILC2s.

NK cells inhibited the expansion and function of ILC2s in vitro via IFN-γ. NK cells inhibited the expansion and function of ILC2s in vitro via IFN-γ. ILC2s.
Foxp3 induction dependent on cell cycle progression in vitro.

Foxp3 induction dependent on cell cycle progression in vitro.
Arterioscler Thromb Vasc Biol

Arterioscler Thromb Vasc Biol
SCLCs and LCNECs are sensitive to PARP inhibition in vitro.

SCLCs and LCNECs are sensitive to PARP inhibition in vitro.
A B C D CD4+ CD8+ Control Isotype Ab Anti-TNFa Ab Control Isotype Ab

A B C D CD4+ CD8+ Control Isotype Ab Anti-TNFa Ab Control Isotype Ab
A B C Supplementary Figure 1 Group 1 Group 2 Group 3 #1 #2 #3 #4 #5 #6

A B C Supplementary Figure 1 Group 1 Group 2 Group 3 #1 #2 #3 #4 #5 #6
Identification of CD3+CD4−CD8− T Cells as Potential Regulatory Cells in an Experimental Murine Model of Graft-Versus-Host Skin Disease (GVHD)  Fumi Miyagawa,

Identification of CD3+CD4−CD8− T Cells as Potential Regulatory Cells in an Experimental Murine Model of Graft-Versus-Host Skin Disease (GVHD)  Fumi Miyagawa,
A B A B C Supplementary Fig. 8 Supplementary Fig. 9

A B A B C Supplementary Fig. 8 Supplementary Fig. 9
Anti–4-1BB/PD-1 combination enriched CD8+ T cells in TILs

Anti–4-1BB/PD-1 combination enriched CD8+ T cells in TILs
Thymic Selection by a Single MHC/Peptide Ligand

Thymic Selection by a Single MHC/Peptide Ligand
Ting-ting Zhang, MSc, Klaus Okkenhaug, PhD, Baher F

Ting-ting Zhang, MSc, Klaus Okkenhaug, PhD, Baher F
Inhibition of Th1 Differentiation by IL-6 Is Mediated by SOCS1

Inhibition of Th1 Differentiation by IL-6 Is Mediated by SOCS1
Cytokine and chemokine expression of flucloxacillin-specific T cell clones (TCC) of patient P1. Cytokine and chemokine expression of flucloxacillin-specific.

Cytokine and chemokine expression of flucloxacillin-specific T cell clones (TCC) of patient P1. Cytokine and chemokine expression of flucloxacillin-specific.
Ravinder S. Chana, David C. Wheeler  Kidney International 

Ravinder S. Chana, David C. Wheeler  Kidney International 
by Éric Aubin, Réal Lemieux, and Renée Bazin

by Éric Aubin, Réal Lemieux, and Renée Bazin

Similar presentations

Ads by Google