1. Comparison of intraocular lens power calculation formulas with LENSTAR LS 900® Tsunekazu Hamada Hamada Eye Clinic, Osaka, Japan Disclosure statement of Financial Interest: Nothing to disclose

2. Purpose & Methods Purpose: To evaluate the accuracy of Olsen formula and commonly used three other intraocular lens power calculation formulas (SRK/T, Haigis, Hollady 2) using LenSTAR LS 900 Methods: The parameters were measured using LenSTAR LS 900 Abbott Medical Optics aspheric: Tecnis ZCB00V was studied At the 2-months post operative visit, apparent refractive results were obtained The prediction error and absolute prediction error were evaluated Off-set error was canceled out such that a mean postoperative refractive error of zero resulted

3. Clinical data of 204 eyes 130 patients 204 eyes Axial length(mm) 24.72±1.7621.79-29.89 K Reading(D)42.84 ±1.4739.05-46.63 ACD(mm) 3.22±0.442.08-4.21 Lens Thickness(mm) 4.44±0.443.37-5.65 Olsen: C-constant = 4.6(PhacoOptics) Haigis:A0 = -0.599, A1 = 0.311, A2 = 0.208(ULIB) SRK/T:A-constant = 119.9(personalized with HIC SOAP) Holladay 2:ACD constant = 5.97(personalized with HIC SOAP) IOL constants

4. Prediction Error ParameterHolladay 2SRK/THaigisOlsen N = 204 ME ±SD(D)0 ± 0.480 ± 0.460 ± 0.420 ± 0.37 MAE(D)0.390.370.340.29 MedAE(D)0.320.310.300.24 <0.5D(%)68.673.074.083.8 <1.0D(%)95.697.199.099.5 MAE = mean absolute error; ME = mean arithmetic error; MedAE = median absolute error; SD = standard deviation of the error Wilcoxon signed-ranks test revealed significant difference in MAEs between Olsen and Holladay 2 (p=0.0001), SRK/T (p=0.0003), Haigis (p=0.0027)

5. Formula bias with the axial length was observed with Haigis, SRK/T and Holladay 2. No formula bias with the axial length was observed with Olsen. Prediction Error

6. Conclusions Olsen formula is more accurate than Haigis, SRK/T and Holladay 2. Formula bias with the axial length was observed with Haigis, SRK/T and Holladay 2. No formula bias with the axial length was observed with Olsen.