1. Good Morning!!

2. Common Causative Agents: Procainamide Hydralazine Penicilliamine (But you can also see drug-induced SLE with phenytoin, methimazole and many other medications)

3. Hypothyroidism

4. Congenital Hypothyroidism

5. Definition

6. Epidemiology

7. *Etiology

8. *Etiology (con’t)

9. *Symptoms and Signs

10. Laboratory Testing

11. *Management

12. *Management (con’t)

13. *Prognosis

14. Acquired Hypothyroidism

15. Epidemiology

16. *Causes of Acquired Hypothyroidism Hashimoto (AI) thyroiditis Postablation Irradiation to the neck Medications Iodine deficiency Late onset congenital hypothyroidism Secondary/ Tertiary Craniopharyngioma Neurosurgery Cranial irradiation Head Trauma

17. *Signs and Symptoms

18. Growth failure

19. *Lab Evaluation

20. Management

21. Prognosis

22. Other entities…

23. Thanks for your attention!