1. Today: and F 4/10 no class. M 4/13 class + movie at 7pm in WEL 1.308

3. Fig 44.25 B-cells, T- cells, antibodies, nutrients, waste, O 2, CO 2, water, minerals, etc must be transported throughout the body

4. Fig 44.24+.25 Mammals have two ciculatory circuits: pulmonary and systemic

5. Fig 44.22 Blood flows from arteries to capillaries to veins

6. Capillaries provide the large surface area required for these exchanges to take place.

7. Fig 44.30 Blood pressure changes as the blood moves from arteries to capillaries

8. Fig 44.23 This change in pressure causes fluid to leak out of the capillaries

9. High pressure, Fluid forced out Blood in vein, More viscous Interstitial fluid, Recovered by…

10. Fig 44.23 Not all of the fluid (~15%) is reabsorbed on the venous side. This interstitial fluid is collected by the lymphatic system.

11. Lymphatic system

12. Fig 44.30 Because of the low pressure in veins and lymph vessels, movement of these fluids comes from skeletal muscles movements.

13. The mammalian circulatory system is both open and closed Fig 44.3

14. Nutrients, Waste, O 2, CO 2, Water, Minerals, etc must be transported throughout the body

15. Fig 44.11 Gases move by diffusion: Only from high to low concentration

16. Fig 44.15 hemoglobin Hb is carried inside red blood cells Hemoglobin (a protein) carries oxygen in the blood

17. Fig 44.11 The Respiratory System: large surface area to maximize gas exchange ~100m 2 in humans

18. Fig 44.11 Gas exchange occurs in alveoli

19. In the lungs, O 2 diffuses into the blood, and CO 2 diffuses out into the lungs.

20. Fig 44.1 How is oxygen delivered to where it is needed?

21. By adjusting blood flow…

22. Fig 44.20 By changes in blood pH

23. Cell Blood Lung CO2 O2 Cellular Respiration Hb in RBC CO2 O2 Hb in RBC Low CO2 High O2 Fig 44.20 O2

24. Cell Blood Lung CO2 O2 Cellular Respiration Hb in RBC CO2 O2 Hb in RBC Low CO2 High O2 CO2+H2O =H2CO3 (carbonic acid) (less carbonic acid) Fig 44.20 O2

25. Cell Blood Lung CO2 O2 Cellular Respiration Hb releases O2 at lower pH CO2 O2 Hb can bind O2 Low CO2 High O2 CO2+H2O =H2CO3 (carbonic acid) (less carbonic acid) Fig 44.20 O2

27. Next week: Nutrition and Digestion F 4/10 no class. M 4/13 class + movie at 7pm in WEL 1.308