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An evolutionarily conserved program of B-cell development and activation in zebrafish by Dawne M. Page, Valerie Wittamer, Julien Y. Bertrand, Kanako L.

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Presentation on theme: "An evolutionarily conserved program of B-cell development and activation in zebrafish by Dawne M. Page, Valerie Wittamer, Julien Y. Bertrand, Kanako L."— Presentation transcript:

1 An evolutionarily conserved program of B-cell development and activation in zebrafish by Dawne M. Page, Valerie Wittamer, Julien Y. Bertrand, Kanako L. Lewis, David N. Pratt, Noemi Delgado, Sarah E. Schale, Caitlyn McGue, Bradley H. Jacobsen, Alyssa Doty, Yvonne Pao, Hongbo Yang, Neil C. Chi, Brad G. Magor, and David Traver Blood Volume 122(8):e1-e11 August 22, 2013 ©2013 by American Society of Hematology

2 Flow cytometric and gene expression analysis of IgM1:eGFP zebrafish. Dawne M. Page et al. Blood 2013;122:e1-e11 ©2013 by American Society of Hematology

3 IgM expression during development. Dawne M. Page et al. Blood 2013;122:e1-e11 ©2013 by American Society of Hematology

4 B-cell ontogeny in IgM1:eGFP fish. Dawne M. Page et al. Blood 2013;122:e1-e11 ©2013 by American Society of Hematology

5 Analysis of IgM+ B cells during an immune response. Dawne M. Page et al. Blood 2013;122:e1-e11 ©2013 by American Society of Hematology

6 Zebrafish B cells are marginally phagocytic. Dawne M. Page et al. Blood 2013;122:e1-e11 ©2013 by American Society of Hematology

7 Isolation and analysis of plasma B cells in zebrafish. Dawne M. Page et al. Blood 2013;122:e1-e11 ©2013 by American Society of Hematology


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