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Circulatory system
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General outline Heart Arteries Capillaries veins Blood vascular system
Lymphatic capillaries Lymphatic vessel Lymphatic ducts Lymphatic vascular system
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Capillaries A single layer of endothelial cells basement membrane
A few connective tissue (pericytes) LM Continuous capillary Fenestrated capillary Sinusoid EM
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Capillaries Continuous C. Fenestrated C. Sinusoid
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Continuous capillary:
distributed in muscle tissue, brain, lung and connective tissue, etc. endothelial cell: large number of pinocytotic vesicles, no pores, exist cell junctions between the endothelia basement membrane: integrity
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Continuous capillary
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Fenestrated capillary:
distributed in the kidney glomerulus, mucosa of gastrointestine, some endocrine glands endothelial cells: present abundant pores, have or haven’t diaphragm on them basement membrane: continuous
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Fenestrated capillary
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Sinusoid: distributed in liver, spleen, and some endocrine glands
a greatly enlarged diameter endothelial cell: intercellular clefts are large between cells, many pores without diaphragm absence of a continuous basement membrane
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Sinusoid
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Artery transport blood from heart to capillaries
according to their size, structure and function Large artery Medium-sized artery Small artery arteriole are classified
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Medium-sized artery: muscular artery Endothelium
Subendothelial layer: LCT Internal elastic lamina: clear Tunica intima Tunica media: contain 10~40 layers of circular smooth muscle External elastic lamina LCT: contain vasa vasorum Tunica adventitia
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Medium-sized artery
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Large artery: elastic artery
subendothelial layer is thicker with a few smooth muscles tunica media is thick, contains a lot of circular elastic membrane internal and external elastic lamina are not distinguished tunica adventitia are thiner
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Large artery
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Small artery: muscular artery and peripheral resistance vessel
internal elastic lamina is clear, while external elastic lamina is not distinguished the media contains 3~9 layers of smooth muscles
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Vein large lumen, thin wall, irregular
internal and external elastic lamina are not clear tunica media is thin, with a few elastic fibers and smooth muscles tunica adventitia is thick some veins have valves
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Heart a muscular organ that contracts rhythmically
pump blood through the circulatory system
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The wall of heart Endothelium Subendothelial layer
Subendocardial layer endocardium myocardium: thickest layer, consists of cardiac muscle LCT: contain adipose tissue Methothelium epicardium
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Impulse generating and conducting system of the heart:
Pacemaker cells: heartbeat generating Purkinje cells (bundle cell): distributed in subendocardial layer, larger than cardiac muscle cells Transitional cells: transmit impulse
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Purkinje cell Cardiac cell
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