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Dynamic Reprogramming of the Kinome in Response to Targeted MEK Inhibition in Triple-Negative Breast Cancer James S. Duncan, Martin C. Whittle, Kazuhiro.

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Presentation on theme: "Dynamic Reprogramming of the Kinome in Response to Targeted MEK Inhibition in Triple-Negative Breast Cancer James S. Duncan, Martin C. Whittle, Kazuhiro."— Presentation transcript:

1 Dynamic Reprogramming of the Kinome in Response to Targeted MEK Inhibition in Triple-Negative Breast Cancer James S. Duncan, Martin C. Whittle, Kazuhiro Nakamura, Amy N. Abell, Alicia A. Midland, Jon S. Zawistowski, Nancy L. Johnson, Deborah A. Granger, Nicole Vincent Jordan, David B. Darr, Jerry Usary, Pei-Fen Kuan, David M. Smalley, Ben Major, Xiaping He, Katherine A. Hoadley, Bing Zhou, Norman E. Sharpless, Charles M. Perou, William Y. Kim, Shawn M. Gomez, Xin Chen, Jian Jin, Stephen V. Frye, H. Shelton Earp, Lee M. Graves, Gary L. Johnson Cell Volume 149, Issue 2, Pages 307-321 (April 2012) DOI: 10.1016/j.cell.2012.02.053 Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

2 Figure 1 Cell 2012 149, 307-321DOI: (10.1016/j.cell.2012.02.053) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

3 Figure 2 Cell 2012 149, 307-321DOI: (10.1016/j.cell.2012.02.053) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

4 Figure 3 Cell 2012 149, 307-321DOI: (10.1016/j.cell.2012.02.053) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

5 Figure 4 Cell 2012 149, 307-321DOI: (10.1016/j.cell.2012.02.053) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

6 Figure 5 Cell 2012 149, 307-321DOI: (10.1016/j.cell.2012.02.053) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

7 Figure 6 Cell 2012 149, 307-321DOI: (10.1016/j.cell.2012.02.053) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

8 Figure 7 Cell 2012 149, 307-321DOI: (10.1016/j.cell.2012.02.053) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

9 Figure S1 Cell 2012 149, 307-321DOI: (10.1016/j.cell.2012.02.053) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

10 Figure S2 Cell 2012 149, 307-321DOI: (10.1016/j.cell.2012.02.053) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

11 Figure S3 Cell 2012 149, 307-321DOI: (10.1016/j.cell.2012.02.053) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

12 Figure S4 Cell 2012 149, 307-321DOI: (10.1016/j.cell.2012.02.053) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

13 Figure S5 Cell 2012 149, 307-321DOI: (10.1016/j.cell.2012.02.053) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

14 Figure S6 Cell 2012 149, 307-321DOI: (10.1016/j.cell.2012.02.053) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

15 Figure S7 Cell 2012 149, 307-321DOI: (10.1016/j.cell.2012.02.053) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

16 Cell 2012 149, 307-321DOI: (10.1016/j.cell.2012.02.053) Copyright © 2012 Elsevier Inc. Terms and Conditions Terms and Conditions

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