1. CTSA KFC Meeting October 28, 2009 UIC Center for Clinical and Translational Science (CCTS): Biomedical Informatics Core

2. BI Core Aims 1.Create an innovative web-based biomedical informatics infrastructure (BII) 2.Develop and integrate clinical data (CRDW) 3.Centralize informatics support services and coordinate education resources A World-Class Education, A World-Class City

3. BI Core Organization Director Denise Hynes, PhD, RN Internal Advisory Board Clinical/Architecture/User Advisory Subcommittees CCTS Program Liaison Melissa Garrett Associate Director for Infrastructure Dev. Ian Brooks, PhD Associate Director for Clinical Research Data Resources Denise Hynes, PhD, RN Associate Director for Education and Consultant Services Annette Valenta, DrPh IT Consultant Bernie Acs Senior Developer Database Analyst/Programmer Graduate Asst Senior Developer Fede Bassetti Social Network Developer Alex Yahja, PhD Usability Expert Andrew Wadsworth, PhD IRD Programmer Graduate Asst Lead Biomedical Informatician Jie Liang, PhD Lead Clinical Informatician Andrew Boyd, PhD Graduate Asst

4. BIOMEDICAL INFORMATICS INFRASTRUCTURE (BII) Status Update – October 2009 A World-Class Education, A World-Class City

5. BII Performance Measures BII Development # components of BII successfully developed Workflow systems in place for each core & updated on a regular basis Central database for workflow tracking in place & updated on a regular basis Informatics support services user statistics available through BII Social networking database functioning & updated on a regular basis Systems & services user feedback

6. BI Infrastructure Development Work Flow & Forms Development Developing Workflow for each Core Extended DAC workflow forms and linked to database Continued refining, testing, & validating DAC service request form functionalities Started working on BI service request forms Started working on RSAC service request forms Transitioning to production software staging Developing basic data viewers Investigating open source scheduling software for CIC Set up scheduling software on development server Provided consultation on CCTS website usability and design A World-Class Education, A World-Class City

7. Progress: Develop and integrate tools for analyzing investigator networks Continued refinement & population of Interactive Researcher Directory (IRD) including: 4,165 Total PIs 1,584 PIs with Active Awards 19,353 Total Grants 22,063 Publications 460,888 MeSH Author Pairs Preliminary integration of CI-KNOW in BII & IRD A World-Class Education, A World-Class City

10. Goal for 2010 annual report & performance metrics BII New Website functioning & statistics on use Workflow forms and database functions fully operational for three cores & statistics on use Preliminary results from social networking analysis using IRD

11. CLINICAL DATA RESOURCES DEVELOPMENT Status Update – October 2009 A World-Class Education, A World-Class City

12. Clinical Data Resources Performance Measures CRDW established and updated on a regular basis Governance structure established and working groups meeting regularly # data domains/sets/elements extracted from EHR to CRDW # requests/users of CRDW data User feedback/evaluation OPRS feedback/evaluation

13. CRDW Development Data architecture with Cerner PowerInsights EDW as bridge between UIMCC EHR to the CRDW in development Planning meetings with UIMCC CIO/IS Calls with CTSA Sites w/Cerner EHR Discussions with Advocate Site visits Clinical Advisory Committee- Plan and prioritize content and usability Architecture Planning Committee - Plan structure User Committee – Advise on research user interface

14. UIMCC’s Current Cerner Database Cerner Enterprise Data Warehouse PHS Etc. MARS PHS Cerner’s Extract Transform Load Research Warehouse Research Warehouse Research Data Warehouse Routine Operational Reporting ER Nursing Pharmacy Radiology Websphere Business Objects All Components Hosted in the UIMCC Data Center UIMCC Firewall UIMCC-IS writes these extracts IRB-approved Researchers CCTS Web-based Research Portal (BII) UIMCC Users UIMCC Data Center

15. Goal for 2010 annual report & performance metrics Clinical Data Resources Completion of Phase 0 Content and ETL plan developed with feedback from faculty/PI Clinical and Architecture Committee priorities

16. CONSULTING/EDUCATION Status Update – October 2009 A World-Class Education, A World-Class City

17. BI Consult/Education Performance Measures Educational programs coordinated and underway # formal presentations # BI education courses developed # persons trained Student/faculty/staff/partner feedback & evaluation Consulting Service operational and processes coordinated with CCTS Admin # consultation services provided # new collaborations initiated # informatics research collaborations or projects initiated A World-Class Education, A World-Class City

18. CCTS BI Core Faculty Consultants: Broad Range of Applied Areas Medicine Psychiatry Urology IDS Bioengineering CS Math Stats & Computer Science Family Medicine OB/Gyn Communication EVL Mechanical & Industrial Engineering Pharmacy Medical Education Business Administration Psychology Epidemiology

19. Goal for 2010 annual report & performance metrics Consulting/Education Consulting service active & operational; statistics on use BHIC Colloquia continuing & statistics on attendees Coordination between health informatics and bioinformatics Development of new course – BHIS 509: Informatics for the Clinical Researcher

20. Support BI Can Provide/Participate Software consultation E.g., CIC consults Data resources advice Advise on software/tracking systems investments and/or development Educational program collaboration/coordination Educ program/academic depts Consult services collaboration/coordination DAC, TTRC