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TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer’s β-Amyloid Oligomers in Mice and Monkeys Mychael V. Lourenco,

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Presentation on theme: "TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer’s β-Amyloid Oligomers in Mice and Monkeys Mychael V. Lourenco,"— Presentation transcript:

1 TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer’s β-Amyloid Oligomers in Mice and Monkeys Mychael V. Lourenco, Julia R. Clarke, Rudimar L. Frozza, Theresa R. Bomfim, Letícia Forny-Germano, André F. Batista, Luciana B. Sathler, Jordano Brito-Moreira, Olavo B. Amaral, Cesar A. Silva, Léo Freitas-Correa, Sheila Espírito-Santo, Paula Campello-Costa, Jean-Christophe Houzel, William L. Klein, Christian Holscher, José B. Carvalheira, Aristobolo M. Silva, Lício A. Velloso, Douglas P. Munoz, Sergio T. Ferreira, Fernanda G. De Felice Cell Metabolism Volume 18, Issue 6, Pages 831-843 (December 2013) DOI: 10.1016/j.cmet.2013.11.002 Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

2 Figure 1 Cell Metabolism 2013 18, 831-843DOI: (10.1016/j.cmet.2013.11.002) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

3 Figure 2 Cell Metabolism 2013 18, 831-843DOI: (10.1016/j.cmet.2013.11.002) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

4 Figure 3 Cell Metabolism 2013 18, 831-843DOI: (10.1016/j.cmet.2013.11.002) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

5 Figure 4 Cell Metabolism 2013 18, 831-843DOI: (10.1016/j.cmet.2013.11.002) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

6 Figure 5 Cell Metabolism 2013 18, 831-843DOI: (10.1016/j.cmet.2013.11.002) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

7 Figure 6 Cell Metabolism 2013 18, 831-843DOI: (10.1016/j.cmet.2013.11.002) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

8 Figure 7 Cell Metabolism 2013 18, 831-843DOI: (10.1016/j.cmet.2013.11.002) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

9 Cell Metabolism 2013 18, 831-843DOI: (10.1016/j.cmet.2013.11.002) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

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