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http://www.kenyanview.com/IMG_0865_Nairobi_skyline.jpg http://www.planetware.com/i/photo/amboseli-national-reserve-formerly-amboseli-national-park-ken132.jpg
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Patient Presentation 22 year old female 22 year old female Sudden onset of severe, watery diarrhea Sudden onset of severe, watery diarrhea Nausea, vomiting Nausea, vomiting Physical exam: dry mouth, low blood pressure Physical exam: dry mouth, low blood pressure
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http://upload.wikimedia.org/wikipedia/commons/thumb/d/db/Vibrio_cholerae_01.jpg/800px-Vibrio_cholerae_01.jpg http://microbewiki.kenyon.edu/images/a/a8/V_cholerae.jpg
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http://www.msf.org/source/countries/africa/angola/2006/cholera_tent.jpg
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You are the doctor, and you must save the patient’s life. Here is what you have to work with… Antiviral medication Antiviral medication Antibacterial medication (antibiotics) Antibacterial medication (antibiotics) Salt Salt Aspirin Aspirin Sugar Sugar Water Water Pepsi Pepsi
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http://www.medicalook.com/systems_images/Digestive_System.jpg
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http://visiblehuman.epfl.ch/
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Skin Intestine Body
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Skin Intestine Body Salt
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Skin The Body Our Model System Conical Tube Dialysis Tube Intestine
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Two Dialysis Tubes per Group Dialysis Tube Conical Tube Dialysis Tube
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Two Dialysis Tubes per Group Conical Tube = water = sucrose
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What happened to the dialysis tube with 80% sucrose? Why?
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Sucrose Solution Water Osmosis
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Osmosis Net Flow of Water
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Sucrose Solution Net Flow of Water
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How does your experiment explain cholera diarrhea?
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Salt
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Net Flow of Water
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How would you treat the patient using osmosis?
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Salt Sugar Salt Sugar Salt Sugar Salt Sugar
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Salt Sugar Salt Sugar Salt Sugar Salt Sugar Salt Sugar Salt Sugar Salt Sugar Net Flow of Water
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