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Jimmy Stewart, MD Professor of Medicine and Pediatrics Division of General Internal Medicine and Hypertension Program Director, Med/Peds Program University of Mississippi Medical Center
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Screening Vaccinations Prophylaxis Education
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All adult ages 50-75 yo 40+ or 10 years prior to relative FOBT, flex sig for “average risk” Colonoscopy - every 5-10 years for high risk
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PSA - NOT recommended for routine screening Greatest sens in AA or high risk group
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High Risk (CAD or equivalent) – statin LDL > 190 mg/dL – statin ASCVD risk > 7.5 % - statin
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MMR* Oral Polio Nasal influenza Yellow fever Smallpox Typhoid BCG Varicella (including Zostavax)
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HBV Influenza Pneumococcal Hib MMR/Td
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Asplenia >65 yo every 5 years Chronic disease (including DM)
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Yearly >50 yo Healthcare workers Childcare workers Household contacts of above
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>55 yo? History of zoster not important
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Meningococcal - not against “B”, college freshmen Cholera - DOESN’T WORK
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Flouroquinolones Azithromycin Must take daily
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Mild: 1-2 stools/day - loperamide Mod: 3 stools/day - single dose Abx Sev: 6 stoos/day - Abx x 3 days with loperamide
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Flouroquinolones Azithromycin
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Chloroquine-resistant - Mefloquin (neuro SE’s) Chloroquine Others - doxy, primaquine, azithromycin
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Gray - resistant; Blue - sensitive
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Rifampin Cipro Rocephin - pregnancy
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Smoking cessation Firearm safety Bladder Cancer Folate supplementation Osteoporosis CVA
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Isopropyl (rubbing alcohol) Methanol (wood alcohol) Ethylene Glycol Salicylates Acetaminophen Theophylline Lithium Tricyclics PCP Anticholinergics Cholinergics CO Cyanide Pb Insecticides
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CNS depression Osmolal gap Early lavage Hemo/peritoneal dialysis
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Visual changes AG met acidosis Treat with ETOH, folate, dialysis, fomepizole
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Ca oxalate crystals AG met acidosis Treat with ETOH, bicarb, calcium, dialysis, fomepizole
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Calcium Oxalate: “folded box”
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AG met acidosis Classic presentation: AG with pH 7.4 and history Treatment - lavage, alkalinization, hemodialysis, charcoal
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N - acetylcysteine Early gastric emptying Normogram
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Seizures Treat with diazepam, lavage, charcoal, cathartic
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MS changes, Parkinsonian DO NOT GIVE CHARCOAL Lavage, electrolytes/fluids, hemodialysis
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Tachycardia, long QT, PR, QRS Hemodialysis INEFFECTIVE Alkalize Lidocaine/phenytoin
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Agitation, seizures, dystonia, HTN Give ammonium Cl to acidify the urine Diazoxide for HTN
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“Red as a beet, dry as a bone, blind as a bat, mad as a hatter, and hot as a hare” Supportive care Physostigmine
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Scopolamine Antihistamines Antipsychotics Antispasmotics Cyclic antidepressants Mydriatics
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“SLUDGE” “DUMBELS” Skin cleansing Atropine 2-PAM for organophosphates
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CNS depression mild-mod: 15-30% mod-sev: >30% Fatal: >50% O2
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Almond breath, bright red venous blood Amyl nitrate 3% Na nitrite Sodium thiosulfate
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Autonomy Beneficence Nonmaleficence Cultural differences Confidentiality Brain death - NO EEG REQUIRED!
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Clinical Risk Functional Capacity Risk of Surgery
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History PE ECG (men >40 yo, women >55 yo, CAD)
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Excellent: >7 METs Moderate: 4-7 METs (angina walking >2 blocks) Poor <4 METs (angina walking 1-2 blocks)
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Low - endoscopy, local biopsy, breast biopsy, vasectomy, cataract Mod - CEA, intraperitoneal, intrathoracic, orthopedic, prostate, head and neck High - emergencies, long procedures/fluid shifts, CVS (cross- clamping aorta or bypass
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Moderate risk with poor functional capacity Moderate risk with good functional capacity and high risk surgery High Risk - all
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Exercise stress treadmill Dipyridamole thallium Dobutamine stress echo
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Low risk patient goes directly to surgery without testing Moderate risk patient with good functional capacity goes directly to nonvascular surgery High risk patient need further workup
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Glaucoma Retinal Detachment Retinal Vascular Occlusion Optic Neuritis Vitreous Hemorrhage Alkali/Trauma Iridocyclitis Keratoconjunctivitis Viral conjunctivitis Bacterial conjunctivitis Neisseria conjunctivitis Endophthalmitis
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Asian American with severe acute nausea, headache while in movie theater Ocular emergency Pupillary constriction
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Acute trauma to head/globe Flashes/streaks of light, showers of black dots Ocular emergency
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Sudden, PAINLESS BLINDNESS Mostly embolic Ocular emergency
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Ocular pain with eye movement, loss of vision MS
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Sudden painless loss of vision Must look for retinal detachment
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VA Anterior chamber: hyphema, corneal laceration, subconjunctival hemorrhage, pupil distortion Irrigation for alkali Referral
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VA decreased Pain Photophobia Pre-auricular adenopathy Discharge
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Ocular pain, photophobia, ciliary flush Emergent referral Behcet’s AK IBD JRA Reiter’s Syndrome Sarcoid Syphillis TB Lyme disease
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Elderly, middle-age women Graves disease RA Sarcoid
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Most common cause of red eye Pre-auricular LAD
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Staph, strep, H. flu, Pseudomonas, Moraxella Antibiotic treatment: Polytrim, gent, tobra, fluoroquinolones
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Hyperacute course MUST TREAT WITH SYSTEMIC ABX! 3rd generation Cephalosporin IM/IV
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Eye pain with movement Chemosis Hypopyon Fever Eye discharge
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Alkali Trauma Orbital Cellulitis Central retinal artery occlusion Acute angle closure glaucoma Optic nerve infarction in giant cell arteritis
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Penetrating injury Endophthalmitis Retinal detachment Keratitis/keratoconjunctivitis
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Cental Retinal vein occlusion Optic neuritis Vitreous detachment/hemorrhage
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