1. Thermo Scientific Blood Banking Solutions Vinod Barot Sr. Product Manager, Centrifugation 14 September 2012

2. 2 Proprietary & Confidential Thermo Fisher Scientific Our size and stability give you a long-term partner: Nearly $12 billion in revenues Approximately 37,000 employees in 40 countries 350,000 customers 150 countries served by 10,500 sales and service personnel We are the leading provider of analytical instruments, equipment, reagents, and consumables, software and services for research, analysis, discovery and diagnostics Leading Brands The world leader in serving science

3. 3 Proprietary & Confidential Meeting the world’s increasingly complex challenges Our Company Mission Enable Our Customers to Make the World… Healthier Cleaner Safer

4. 4 Proprietary & Confidential Blood Banking Workflow PROCESSING SAMPLE PREPARATION TESTINGSTORAGE BLOOD BANKING WORKFLOW

5. 5 Proprietary & Confidential Thermo Scientific Cryofuge 6000i Flexibility Wind Shielded rotor: reduce friction Choice of adapters for different blood bag sizes HERANET software for traceability of blood bags

6. 6 Proprietary & Confidential Cryofuge 6000i: 12 Bag Centrifuge

7. 7 Proprietary & Confidential Advantages of Wind Shield Rotor Reduced air friction helps in reduction of heat and noise Reduction in air friction helps in reduction of power consumption. By using relatively less powerful drive motor and refrigeration system. with non wind shielded rotor which often needs 400V, 3 phase supply with approx 2.5 times more power consumption UNIFORM TEMPERATURE - Due to wind shield (close environment) the temperature accuracy and uniformity is better which results into high quality components. (The WHO Cold Chain Project defines the need of uniform temperature during the complete process) less stress on samples helps to retain integrity of samples Operator safety incase of bag ruptures

8. 8 Proprietary & Confidential liners for bucket 7500 7617 M:double bags L:triple bags quad bags XL:quadruple bags (soft filter) XXL: quintuple bags filter bags (hard plastic filter) XXL L XL M Accessories

9. 9 Proprietary & Confidential Separation of blood components by means of centrifugation – Cord Blood Processing Holder for blood bags 7501 5638 (5652) „Hook-Adapter“ for bucket 7617 / 6436

10. 10 Proprietary & Confidential Cryofuge 5500i 8 Bag Centrifuge  High Performance,Extreme Reliability  Compact Design, Easy to use  Intuitive Controls  8 blood bags in a single run

11. 11 Proprietary & Confidential Multifuge 4 KR 4 Bag Centrifuge

12. 12 Proprietary & Confidential Purpose To test and screen blood samples to ensure safety of blood supply Requirement Efficient and safe process Instrumentation Clinical benchtop centrifuges Instrument criteria Optimal throughput Biosafe certified containers Easy-to-use control panel BLOOD SAMPLE PREPARATION

13. 13 Proprietary & Confidential Thermo Scientific Solutions Comprehensive range of benchtop centrifuges from small scale of 8-12 to super capacity of 196 10ml blood tubes and microplates Features Biocontainment certified ClickSeal bucket system and rotor lid Super capacity BIOLiner rotor accommodating upto 196 blood tubes in single run Various choice of adapters for different blood tube types Products 1L/3L general purpose benchtop centrifuges Small bench clinical centrifuges

14. 14 Proprietary & Confidential Purpose To ensure safety and quality of blood supply Requirement Accuracy and reproducibility of routine testing procedures Instrumentation Pipetting systems Automated liquid handling Microplate handling systems Instrument criteria High throughput Precise volume control Accurate assay analysis BLOODTESTING

15. 15 Proprietary & Confidential Thermo Scientific Solution Manual and electronic pipetting systems Features Antimicrobial surface protection prevents contamination Adjustable finger rest Multiple pipetting functions and speeds Pipette tips available in standard, filter, sterile and non-sterile Products Manual pipettes Electronic pipettes Pipette tips and consumables

16. 16 Proprietary & Confidential ThermoFisher - Solution for NAT Liquid Handling Pipettes & Dispensers KingFisher Technology DNA/RNA isolation Analysis PCR / RealTime PCR KITS for sample preparations or

17. 17 Proprietary & Confidential Microplate Instrumentation Microplate instrumentations and consumables for efficient serological assay and reporting Features Wide wavelength range 340-850nm Easy-to-use visual user interface and multiple language versions Exceptional temperature uniformity UV transparent microplates in 96- and 384-well formats Products Microplate reader Microplate washer Microplate incubator/shaker Automated DNA purification system Microplates consumables

18. 18 Proprietary & Confidential Types of safety cabinets we address Our Pre Filter A2 is certified by TÜV to DIN 12980 for approved use in cytotoxic drug handling and preparation. TFS Models - Series 1300 - MSC Series - Safe 2020 - HERAsafe KS TFS Models - HERAsafe KSP - MAXisafe 2020 TFS Model - Series 1300 B2 Safety First Proprietary & Confidential

19. 19 Proprietary & Confidential Blood Protection Purpose To preserve blood components until they are needed Requirement Viability of blood components is maintained Instrumentation Refrigerators Plasma freezer Cryopreservation system Instrument criteria Rapid and reliable cooling Temperature uniformity Samples traceability BLOODSTORAGE

20. 20 Proprietary & Confidential Thermo Scientific Solution Comprehensive range of blood bank Cold Storage systems – ULT Freezers Features (PEEK - Performance Ease of use Energy efficient Kapacity) Touch-screen LCD interface (ease of use) On-line health monitoring In-built event logger (15 years data storage) Largest possible storage capacity (949L) Industry leading “footprint to blood bag” ratio Advanced set-point security and access security Data transfer through USB port

21. 21 Proprietary & Confidential Blood Storage Blood Bank Refrigerators/Plasma Freezers/Red cell ULT/Cryogenic Proprietary & Confidential Products +4 °C blood bank refrigerators -40 °C plasma freezers -80 °C ultra-low temperature freezers Cryopreservation system

22. 22 Proprietary & Confidential Thermo Fisher-Your reliable partner for complete support Calibration Operation Qualification Validation Installation and Training Preventative Maintenance Proof of Performance Replacement parts and repair Temperature mapping

23. 23 Proprietary & Confidential Successful track record as Blood Bank Solution provider Supplied and Maintained Over 800 Blood Bank Centrifuges across the country Supplied to various government blood banks through National Aids Control Organization Over 400 Refrigerated Centrifuges Model Thermo Scientific Heraeus Cryofuge 6000i 765 Elisa System Model Thermo Scientific Lab System Multiscan Reader with Well wash washer Thermo Scientific Jewett Blood Bank Refrigerator

24. 24 Proprietary & Confidential Blood Banking Workflow PROCESSING SAMPLE PREPARATION TESTINGSTORAGE BLOOD BANKING WORKFLOW

25. 25 Proprietary & Confidential Thermo Scientific Solutions LOW SPEED LARGE CAPACITY CENTRIFUGES BENCHTOP CENTRIFUGES PIPETTE PLATE READERS PLATE WASHERS INCUBATORS NUCLIEC ACID PURIFICATION SYSTEM CONSUMABLES 4°C BLOOD BANK REGRIGERATORS -30°C PLASMA FREEZERS -86°C ULTRA LOW TEMPERATURE FREEZER THERMO SCIENTIFIC SOLUTIONS

26. 26 Proprietary & Confidential Summary Thermo Scientific provides essential instruments, consumables, services and software for every stage of the blood bank workflow …

27. 27 Proprietary & Confidential For further discussion- visit us at booth No. 22, 23