1. Breast Cancer

2. Dr. Swapna Chaudhary M.S. (MUM) M.S. (MUM) Consultant Obstetrician & Gynaecologist Infertility Specialist

3. Incidence

4. Incidence  Common cause of cancer in females

5. Incidence  200,000 new cases annually around world

6. Incidence  Common cause of cancer in females  200,000 new cases annually around world  40,000 deaths

7. Risk Factors

8.  Age > 50

9. Risk Factors  Age > 50  High income group

10. Risk Factors  Age > 50  High income group  Family History (mother / sister)

11. Risk Factors  Age > 50  High income group  Family History (mother / sister) (Risk increases if > 1 1 st degree relative affected, bilateral breast disease, young age at diagnosis) (Risk increases if > 1 1 st degree relative affected, bilateral breast disease, young age at diagnosis)

12. Risk Factors  Age > 50  High income group  Family History (mother / sister) (Risk increases if > 1 1 st degree relative affected, bilateral breast disease, young age at diagnosis) (Risk increases if > 1 1 st degree relative affected, bilateral breast disease, young age at diagnosis)  BRCA mutation

13. Risk Factors  Age > 50  High income group  Family History (mother / sister) (Risk increases if > 1 1 st degree relative affected, bilateral breast disease, young age at diagnosis) (Risk increases if > 1 1 st degree relative affected, bilateral breast disease, young age at diagnosis)  BRCA mutation  Nulliparity (no children)

14.  1 st pregnancy after 30 yrs

15.  Early menarche

16.  1 st pregnancy after 30 yrs  Early menarche  Late menopause

17.  1 st pregnancy after 30 yrs  Early menarche  Late menopause  Obesity

18.  1 st pregnancy after 30 yrs  Early menarche  Late menopause  Obesity  Poss. Risk factors – high dietary fat, prolonged use of OCP (>10 yrs), alcohol, stress

19. Screening methods

20. 1.Breast self examination

21. Screening methods 1.Breast self examination 2.Clinical examination

22. Screening methods 1.Breast self examination 2.Clinical examination 3.Mammography

23. Screening methods 1.Breast self examination 2.Clinical examination 3.Mammography  screening method – done for non palpable, early, small (<1cm) tumors in asymptomatic women

24. Screening methods 1.Breast self examination 2.Clinical examination 3.Mammography  screening method – done for non palpable, early, small (<1cm) tumors in asymptomatic women  ‘abnormal mass’ further investigated by additional imaging or biopsy

25.  Screening mammography can detect cancer 2 to 3 yrs before it can become symptomatic (10% cancer still failed to be detected by mammography)

26. 4. FNAC / biopsy

27. Treatment

28. Treatment  Surgical Treatment

29. Treatment  Mastectomy

30. Treatment  Surgical Treatment  Mastectomy  Breast conservation

31. Treatment  Surgical Treatment  Mastectomy  Breast conservation  Lumpectomy with XRT

32. Treatment  Surgical Treatment  Mastectomy  Breast conservation  Lumpectomy with XRT  Equal outcomes!

33. Thank you