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F 6-4 F 6-5 F 6-8 CH 2 NH 2 COOH PHENYLALANINE RATE LIMITING STEP CH 2 PNMT (Phenyl ethanol amine N Methyl transferase) HO CCH 2 H.

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Presentation on theme: "F 6-4 F 6-5 F 6-8 CH 2 NH 2 COOH PHENYLALANINE RATE LIMITING STEP CH 2 PNMT (Phenyl ethanol amine N Methyl transferase) HO CCH 2 H."— Presentation transcript:

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13 CH 2 NH 2 COOH PHENYLALANINE RATE LIMITING STEP CH 2 PNMT (Phenyl ethanol amine N Methyl transferase) HO CCH 2 H N H O H 3 EPINEPHRINE CH 2 NH 2 COOH O TYROSINE HO O DOPAMINE B-OXIDASE HO CCH 2 NH 2 H O H O NOREPINEPHRINE CO CH 2 2 NH 2 HO DOPAMINE 2 CH 2 2 NH 2 HO 2 F 6-10 HO CH 2 NH 2 HO COOH DOPA

14 F 6-11

15 F 6-12

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17 F 6-14

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21 hy no ph cl op Cy en ta er dr op he na nt hr en e

22 2524 1 2 3 4 5 6 7 8 9 10 11 12 13 1415 16 17 18 19 20 21 2223 27 26

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25 F 6-19

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27 STEROID NOMENCLATURE Prefix Suffix Indicates Hydroxy -ol Hydroxyl group (-OH) β-OH - Hydroxyl above plane α-OH - Hydroxyl below plane Oxo one Keto or carbonyl group (C=O) - al Aldehyde (-CHO) Carboxy -oic acid Carboxylic acid (COOH) - -ene Double bond (-C=C-) - -yne Triple bond (-C=C-) - -ane Saturated ring

28 H C 3 H CH C 3 C CH O OH 2 3 4 11 17 20 21 PREGN-4-ENE-3, 20 DIONE, 11β, 17α, 21 TRIOL CORTISOL F 6-22 O

29 F 6-23 Arachidonic acid Prostaglandin E Cyclooxygenase

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32 F 6-26

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36 F 6-28

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43 NUMBER OF SITES No response Response F 6-34

44 SPECIFICITY OF TISSUE No response Response F 6-35

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51 F 6-42

52 ☺☻☺☻

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