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Clinical Guidelines in Acute Seizure Management
William C. Dalsey, MD, FACEP, MBA Department of Emergency Medicine Robert Wood Johnson University Hospital New Jersey
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How Do You Begin to Create a Clinical Guideline for Seizures?
Selecting the Topic Selecting Members of the Committee Process for Evaluating the Literature Process to Create Clinical Guideline
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Critical Questions How do you evaluate and treat a patient with a seizure? Complicating Factors: Status Epilepticus? Hypoglycemia, Febrile Seizures, Alcohol Withdrawal, Trauma, Eclampsia
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What is best? Efficacy of Treatment? Safety?
Complications? Side Effects? Route of Administration? Costs? Society/Ethics?
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Are There Existing Practice Guidelines?
AMA Clinical Guidelines Clearinghouse Cochrane Library
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Asking the “Right” Questions
The need to be specific Identification of inclusion/exclusion criteria Searching the Literature Metanalysis and Nonrandomized Trials
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