1. Welcome Advanced Bioinformatics BIF-30806

2. Content of the course Basic Linux Perl scripting Bioinformatics Software Protein networks Protein Interactions Protein function prediction NGS RNA-seq Comparative genomics Project

3. Teachers Harm Nijveen Sandra Smit Gabino Sanchez Perez Edouard Severing Hendrik-Jan Megens Aalt-Jan van Dijk Elio Schijlen Ke Lin Joachim Bargsten Pjotr Prins Saulo Alves Aflitos Robert Ernst Ioannis Moustakas

4. Grading Exercises(8) + Perl exam30% Project Report50% Project Presentation20% (inter)active participation during lectures and practical sessions is highly appreciated

5. Hours Mornings: 9 - 12 Afternoon: 13 – 17 Coffee/tea breaks as required

6. Project Create an analysis pipeline using Perl to answer a biological question 2 weeks Small teams of ~4 students One report and presention per student

7. Perl Introduction to the language Focus on practical use Exercises numbered 1 - 8 should to be mailed before Feb 15, 17h to: harmn@bioinformatics.nlharmn@bioinformatics.nl Exam at the end of week one