Presentation is loading. Please wait.

Presentation is loading. Please wait.

Pathway-Selective Sensitization of Mycobacterium tuberculosis for Target-Based Whole- Cell Screening Garth L. Abrahams, Anuradha Kumar, Suzana Savvi, Alvin.

Published byNick Foxworthy Modified over 9 years ago

Similar presentations

Presentation on theme: "Pathway-Selective Sensitization of Mycobacterium tuberculosis for Target-Based Whole- Cell Screening Garth L. Abrahams, Anuradha Kumar, Suzana Savvi, Alvin."— Presentation transcript:

1 Pathway-Selective Sensitization of Mycobacterium tuberculosis for Target-Based Whole- Cell Screening Garth L. Abrahams, Anuradha Kumar, Suzana Savvi, Alvin W. Hung, Shijun Wen, Chris Abell, Clifton E. Barry, David R. Sherman, Helena I.M. Boshoff, Valerie Mizrahi Chemistry & Biology Volume 19, Issue 7, Pages 844-854 (July 2012) DOI: 10.1016/j.chembiol.2012.05.020 Copyright © 2012 Elsevier Ltd Terms and Conditions Terms and Conditions

2 Figure 1 Chemistry & Biology 2012 19, 844-854DOI: (10.1016/j.chembiol.2012.05.020) Copyright © 2012 Elsevier Ltd Terms and Conditions Terms and Conditions

3 Figure 2 Chemistry & Biology 2012 19, 844-854DOI: (10.1016/j.chembiol.2012.05.020) Copyright © 2012 Elsevier Ltd Terms and Conditions Terms and Conditions

4 Figure 3 Chemistry & Biology 2012 19, 844-854DOI: (10.1016/j.chembiol.2012.05.020) Copyright © 2012 Elsevier Ltd Terms and Conditions Terms and Conditions

5 Figure 4 Chemistry & Biology 2012 19, 844-854DOI: (10.1016/j.chembiol.2012.05.020) Copyright © 2012 Elsevier Ltd Terms and Conditions Terms and Conditions

6 Figure 5 Chemistry & Biology 2012 19, 844-854DOI: (10.1016/j.chembiol.2012.05.020) Copyright © 2012 Elsevier Ltd Terms and Conditions Terms and Conditions

7 Figure 6 Chemistry & Biology 2012 19, 844-854DOI: (10.1016/j.chembiol.2012.05.020) Copyright © 2012 Elsevier Ltd Terms and Conditions Terms and Conditions

8 Figure 7 Chemistry & Biology 2012 19, 844-854DOI: (10.1016/j.chembiol.2012.05.020) Copyright © 2012 Elsevier Ltd Terms and Conditions Terms and Conditions

Download ppt "Pathway-Selective Sensitization of Mycobacterium tuberculosis for Target-Based Whole- Cell Screening Garth L. Abrahams, Anuradha Kumar, Suzana Savvi, Alvin."

Similar presentations

Halogen Bonds Form the Basis for Selective P-TEFb Inhibition by DRB Sonja Baumli, Jane A. Endicott, Louise N. Johnson Chemistry & Biology Volume 17, Issue.

Halogen Bonds Form the Basis for Selective P-TEFb Inhibition by DRB Sonja Baumli, Jane A. Endicott, Louise N. Johnson Chemistry & Biology Volume 17, Issue.
Binocular rivalry Colin W.G. Clifford Current Biology Volume 19, Issue 22, Pages R1022-R1023 (December 2009) DOI: 10.1016/j.cub.2009.09.006 Copyright ©

Binocular rivalry Colin W.G. Clifford Current Biology Volume 19, Issue 22, Pages R1022-R1023 (December 2009) DOI: /j.cub Copyright ©
Bisubstrate Adenylation Inhibitors of Biotin Protein Ligase from Mycobacterium tuberculosis Benjamin P. Duckworth, Todd W. Geders, Divya Tiwari, Helena.

Bisubstrate Adenylation Inhibitors of Biotin Protein Ligase from Mycobacterium tuberculosis Benjamin P. Duckworth, Todd W. Geders, Divya Tiwari, Helena.
Development of Antibiotic Activity Profile Screening for the Classification and Discovery of Natural Product Antibiotics Weng Ruh Wong, Allen G. Oliver,

Development of Antibiotic Activity Profile Screening for the Classification and Discovery of Natural Product Antibiotics Weng Ruh Wong, Allen G. Oliver,
Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages 12-24 (July 2010) DOI: 10.1016/j.immuni.2010.07.006.

Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni
Regulation of Telomere Length by G-Quadruplex Telomere DNA- and TERRA-Binding Protein TLS/FUS Kentaro Takahama, Asami Takada, Shota Tada, Mai Shimizu,

Regulation of Telomere Length by G-Quadruplex Telomere DNA- and TERRA-Binding Protein TLS/FUS Kentaro Takahama, Asami Takada, Shota Tada, Mai Shimizu,
The Biosynthesis of Teicoplanin-Type Glycopeptide Antibiotics: Assignment of P450 Mono-Oxygenases to Side Chain Cyclizations of Glycopeptide A47934 Bianka.

The Biosynthesis of Teicoplanin-Type Glycopeptide Antibiotics: Assignment of P450 Mono-Oxygenases to Side Chain Cyclizations of Glycopeptide A47934 Bianka.
Analysis of the Ketosynthase-Chain Length Factor Heterodimer from the Fredericamycin Polyketide Synthase Ping-Hui Szu, Sridhar Govindarajan, Michael J.

Analysis of the Ketosynthase-Chain Length Factor Heterodimer from the Fredericamycin Polyketide Synthase Ping-Hui Szu, Sridhar Govindarajan, Michael J.
Proteasome Inhibition by Fellutamide B Induces Nerve Growth Factor Synthesis John Hines, Michael Groll, Margaret Fahnestock, Craig M. Crews Chemistry &

Proteasome Inhibition by Fellutamide B Induces Nerve Growth Factor Synthesis John Hines, Michael Groll, Margaret Fahnestock, Craig M. Crews Chemistry &
Ancient Endo-siRNA Pathways Reveal New Tricks Julie M. Claycomb Current Biology Volume 24, Issue 15, Pages R703-R715 (August 2014) DOI: 10.1016/j.cub.2014.06.009.

Ancient Endo-siRNA Pathways Reveal New Tricks Julie M. Claycomb Current Biology Volume 24, Issue 15, Pages R703-R715 (August 2014) DOI: /j.cub
The Circadian Timekeeping System of Drosophila Paul E. Hardin Current Biology Volume 15, Issue 17, Pages R714-R722 (September 2005) DOI: 10.1016/j.cub.2005.08.019.

The Circadian Timekeeping System of Drosophila Paul E. Hardin Current Biology Volume 15, Issue 17, Pages R714-R722 (September 2005) DOI: /j.cub
Nitric Oxide-Mediated Histone Hyperacetylation in Oral Cancer: Target for a Water- Soluble HAT Inhibitor, CTK7A Mohammed Arif, Bhusainahalli M. Vedamurthy,

Nitric Oxide-Mediated Histone Hyperacetylation in Oral Cancer: Target for a Water- Soluble HAT Inhibitor, CTK7A Mohammed Arif, Bhusainahalli M. Vedamurthy,
Two views of brain function Marcus E. Raichle Trends in Cognitive Sciences Volume 14, Issue 4, Pages 180-190 (April 2010) DOI: 10.1016/j.tics.2010.01.008.

Two views of brain function Marcus E. Raichle Trends in Cognitive Sciences Volume 14, Issue 4, Pages (April 2010) DOI: /j.tics
Accessing Protein Methyltransferase and Demethylase Enzymology Using Microfluidic Capillary Electrophoresis Tim J. Wigle, Laurel M. Provencher, Jacqueline.

Accessing Protein Methyltransferase and Demethylase Enzymology Using Microfluidic Capillary Electrophoresis Tim J. Wigle, Laurel M. Provencher, Jacqueline.
In Vivo Photoswitchable Flow Cytometry for Direct Tracking of Single Circulating Tumor Cells Dmitry A. Nedosekin, Vladislav V. Verkhusha, Alexander V.

In Vivo Photoswitchable Flow Cytometry for Direct Tracking of Single Circulating Tumor Cells Dmitry A. Nedosekin, Vladislav V. Verkhusha, Alexander V.
A Fluorescent Hydrogel-Based Flow Cytometry High-Throughput Screening Platform for Hydrolytic Enzymes Christian Pitzler, Georgette Wirtz, Ljubica Vojcic,

A Fluorescent Hydrogel-Based Flow Cytometry High-Throughput Screening Platform for Hydrolytic Enzymes Christian Pitzler, Georgette Wirtz, Ljubica Vojcic,
Siderophores from Neighboring Organisms Promote the Growth of Uncultured Bacteria Anthony D'Onofrio, Jason M. Crawford, Eric J. Stewart, Kathrin Witt,

Siderophores from Neighboring Organisms Promote the Growth of Uncultured Bacteria Anthony D'Onofrio, Jason M. Crawford, Eric J. Stewart, Kathrin Witt,
Novel Ligands for a Purine Riboswitch Discovered by RNA-Ligand Docking Peter Daldrop, Francis E. Reyes, David A. Robinson, Colin M. Hammond, David M. Lilley,

Novel Ligands for a Purine Riboswitch Discovered by RNA-Ligand Docking Peter Daldrop, Francis E. Reyes, David A. Robinson, Colin M. Hammond, David M. Lilley,
A Dumbbell-Shaped Small Molecule that Promotes Cell Adhesion and Growth Sayumi Yamazoe, Hiroki Shimogawa, Shin-ichi Sato, Jeffrey D. Esko, Motonari Uesugi.

A Dumbbell-Shaped Small Molecule that Promotes Cell Adhesion and Growth Sayumi Yamazoe, Hiroki Shimogawa, Shin-ichi Sato, Jeffrey D. Esko, Motonari Uesugi.
IPSC Crowdsourcing: A Model for Obtaining Large Panels of Stem Cell Lines for Screening Mahendra Rao Cell Stem Cell Volume 13, Issue 4, Pages 389-391 (October.

IPSC Crowdsourcing: A Model for Obtaining Large Panels of Stem Cell Lines for Screening Mahendra Rao Cell Stem Cell Volume 13, Issue 4, Pages (October.

Similar presentations

Ads by Google