Presentation is loading. Please wait.

Presentation is loading. Please wait.

Piperazine and Piperidine Triazole Ureas as Ultrapotent and Highly Selective Inhibitors of Monoacylglycerol Lipase Niina Aaltonen, Juha R. Savinainen,

Published byGracie Cutlip Modified over 10 years ago

Similar presentations

Presentation on theme: "Piperazine and Piperidine Triazole Ureas as Ultrapotent and Highly Selective Inhibitors of Monoacylglycerol Lipase Niina Aaltonen, Juha R. Savinainen,"— Presentation transcript:

1 Piperazine and Piperidine Triazole Ureas as Ultrapotent and Highly Selective Inhibitors of Monoacylglycerol Lipase Niina Aaltonen, Juha R. Savinainen, Casandra Riera Ribas, Jani Rönkkö, Anne Kuusisto, Jani Korhonen, Dina Navia-Paldanius, Jukka Häyrinen, Piia Takabe, Heikki Käsnänen, Tatu Pantsar, Tuomo Laitinen, Marko Lehtonen, Sanna Pasonen-Seppänen, Antti Poso, Tapio Nevalainen, Jarmo T. Laitinen Chemistry & Biology Volume 20, Issue 3, Pages 379-390 (March 2013) DOI: 10.1016/j.chembiol.2013.01.012 Copyright © 2013 Elsevier Ltd Terms and Conditions Terms and Conditions

2 Figure 1 Chemistry & Biology 2013 20, 379-390DOI: (10.1016/j.chembiol.2013.01.012) Copyright © 2013 Elsevier Ltd Terms and Conditions Terms and Conditions

3 Figure 2 Chemistry & Biology 2013 20, 379-390DOI: (10.1016/j.chembiol.2013.01.012) Copyright © 2013 Elsevier Ltd Terms and Conditions Terms and Conditions

4 Figure 3 Chemistry & Biology 2013 20, 379-390DOI: (10.1016/j.chembiol.2013.01.012) Copyright © 2013 Elsevier Ltd Terms and Conditions Terms and Conditions

Download ppt "Piperazine and Piperidine Triazole Ureas as Ultrapotent and Highly Selective Inhibitors of Monoacylglycerol Lipase Niina Aaltonen, Juha R. Savinainen,"

Similar presentations

Sequential Action of Two Flavoenzymes, PgaE and PgaM, in Angucycline Biosynthesis: Chemoenzymatic Synthesis of Gaudimycin C Pauli Kallio, Zhanliang Liu,

Sequential Action of Two Flavoenzymes, PgaE and PgaM, in Angucycline Biosynthesis: Chemoenzymatic Synthesis of Gaudimycin C Pauli Kallio, Zhanliang Liu,
Characterization of the Alnumycin Gene Cluster Reveals Unusual Gene Products for Pyran Ring Formation and Dioxan Biosynthesis Terhi Oja, Kaisa Palmu, Hanna.

Characterization of the Alnumycin Gene Cluster Reveals Unusual Gene Products for Pyran Ring Formation and Dioxan Biosynthesis Terhi Oja, Kaisa Palmu, Hanna.
Loop Grafting of Bacillus subtilis Lipase A: Inversion of Enantioselectivity Ykelien L. Boersma, Tjaard Pijning, Margriet S. Bosma, Almer M. van der Sloot,

Loop Grafting of Bacillus subtilis Lipase A: Inversion of Enantioselectivity Ykelien L. Boersma, Tjaard Pijning, Margriet S. Bosma, Almer M. van der Sloot,
URB754 Has No Effect on the Hydrolysis or Signaling Capacity of 2-AG in the Rat Brain Susanna M. Saario, Ville Palomäki, Marko Lehtonen, Tapio Nevalainen,

URB754 Has No Effect on the Hydrolysis or Signaling Capacity of 2-AG in the Rat Brain Susanna M. Saario, Ville Palomäki, Marko Lehtonen, Tapio Nevalainen,
Attila Andics, Márta Gácsi, Tamás Faragó, Anna Kis, Ádám Miklósi 

Attila Andics, Márta Gácsi, Tamás Faragó, Anna Kis, Ádám Miklósi 
Halogen Bonds Form the Basis for Selective P-TEFb Inhibition by DRB Sonja Baumli, Jane A. Endicott, Louise N. Johnson Chemistry & Biology Volume 17, Issue.

Halogen Bonds Form the Basis for Selective P-TEFb Inhibition by DRB Sonja Baumli, Jane A. Endicott, Louise N. Johnson Chemistry & Biology Volume 17, Issue.
Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages 241-253 (March 2014) DOI: 10.1016/j.cell.2014.02.012 Copyright.

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.
Binocular rivalry Colin W.G. Clifford Current Biology Volume 19, Issue 22, Pages R1022-R1023 (December 2009) DOI: 10.1016/j.cub.2009.09.006 Copyright ©

Binocular rivalry Colin W.G. Clifford Current Biology Volume 19, Issue 22, Pages R1022-R1023 (December 2009) DOI: /j.cub Copyright ©
Development of Antibiotic Activity Profile Screening for the Classification and Discovery of Natural Product Antibiotics Weng Ruh Wong, Allen G. Oliver,

Development of Antibiotic Activity Profile Screening for the Classification and Discovery of Natural Product Antibiotics Weng Ruh Wong, Allen G. Oliver,
Regulation of Telomere Length by G-Quadruplex Telomere DNA- and TERRA-Binding Protein TLS/FUS Kentaro Takahama, Asami Takada, Shota Tada, Mai Shimizu,

Regulation of Telomere Length by G-Quadruplex Telomere DNA- and TERRA-Binding Protein TLS/FUS Kentaro Takahama, Asami Takada, Shota Tada, Mai Shimizu,
Visual Cortex Extrastriate Body-Selective Area Activation in Congenitally Blind People “Seeing” by Using Sounds Ella Striem-Amit, Amir Amedi Current Biology.

Visual Cortex Extrastriate Body-Selective Area Activation in Congenitally Blind People “Seeing” by Using Sounds Ella Striem-Amit, Amir Amedi Current Biology.
Advances in shaking technologies Wolf Klöckner, Jochen Büchs Trends in Biotechnology Volume 30, Issue 6, Pages 307-314 (June 2012) DOI: 10.1016/j.tibtech.2012.03.001.

Advances in shaking technologies Wolf Klöckner, Jochen Büchs Trends in Biotechnology Volume 30, Issue 6, Pages (June 2012) DOI: /j.tibtech
Mucosal Immunology of Food Allergy M. Cecilia Berin, Hugh A. Sampson Current Biology Volume 23, Issue 9, Pages R389-R400 (May 2013) DOI: 10.1016/j.cub.2013.02.043.

Mucosal Immunology of Food Allergy M. Cecilia Berin, Hugh A. Sampson Current Biology Volume 23, Issue 9, Pages R389-R400 (May 2013) DOI: /j.cub
How do emotion and motivation direct executive control? Luiz Pessoa Trends in Cognitive Sciences Volume 13, Issue 4, Pages 160-166 (April 2009) DOI: 10.1016/j.tics.2009.01.006.

How do emotion and motivation direct executive control? Luiz Pessoa Trends in Cognitive Sciences Volume 13, Issue 4, Pages (April 2009) DOI: /j.tics
Neural Activity in the Central Complex of the Insect Brain Is Linked to Locomotor Changes John A. Bender, Alan J. Pollack, Roy E. Ritzmann Current Biology.

Neural Activity in the Central Complex of the Insect Brain Is Linked to Locomotor Changes John A. Bender, Alan J. Pollack, Roy E. Ritzmann Current Biology.
A Gαq-Ca2+ Signaling Pathway Promotes Actin-Mediated Epidermal Wound Closure in C. elegans Suhong Xu, Andrew D. Chisholm Current Biology Volume 21, Issue.

A Gαq-Ca2+ Signaling Pathway Promotes Actin-Mediated Epidermal Wound Closure in C. elegans Suhong Xu, Andrew D. Chisholm Current Biology Volume 21, Issue.
Does the contraceptive pill alter mate choice in humans? Alexandra Alvergne, Virpi Lummaa Trends in Ecology & Evolution Volume 25, Issue 3, Pages 171-179.

Does the contraceptive pill alter mate choice in humans? Alexandra Alvergne, Virpi Lummaa Trends in Ecology & Evolution Volume 25, Issue 3, Pages
Proteasome Inhibition by Fellutamide B Induces Nerve Growth Factor Synthesis John Hines, Michael Groll, Margaret Fahnestock, Craig M. Crews Chemistry &

Proteasome Inhibition by Fellutamide B Induces Nerve Growth Factor Synthesis John Hines, Michael Groll, Margaret Fahnestock, Craig M. Crews Chemistry &
Ancient Endo-siRNA Pathways Reveal New Tricks Julie M. Claycomb Current Biology Volume 24, Issue 15, Pages R703-R715 (August 2014) DOI: 10.1016/j.cub.2014.06.009.

Ancient Endo-siRNA Pathways Reveal New Tricks Julie M. Claycomb Current Biology Volume 24, Issue 15, Pages R703-R715 (August 2014) DOI: /j.cub
The Circadian Timekeeping System of Drosophila Paul E. Hardin Current Biology Volume 15, Issue 17, Pages R714-R722 (September 2005) DOI: 10.1016/j.cub.2005.08.019.

The Circadian Timekeeping System of Drosophila Paul E. Hardin Current Biology Volume 15, Issue 17, Pages R714-R722 (September 2005) DOI: /j.cub

Similar presentations

Ads by Google