1. Report of the POCT Project Aydan Kansu – Turkey

2. Tokat Konya

3. Dr. Ayşe F. Genç KONYA TOKAT - ERBAA Dr. Engin Yurdakul Population: 60.000 Population: 2.500.000

4. Total: 771 children F: 395 (51.2%) M: 376 (48.8%) 11.0 ± 3.3 years School screening: 666 children Outpatients: 105 children

5. Medical History Diarrhea: 6.2% Abdominal discomfort: 18.4% Constipation: 6.6% Vomiting: 6.5% Nausea: 6.7% FTT: 6.6% F to gain weight: 8.5% Abdominal distension: 6.7%

6. Physical Examination Weight 3%  : 0.7% Height 3%  : 1% Pallor: 2.8% Abdominal distension: 0.7% Signs of dystrophy: 0.7% Dermatitis: 2.4%

7. 1.7% 5.1% 27.0% 50.4% 9.0% 5.0% 1.8%

8. Biochemical assessment Concomitant therapies

9. POCT +: 1/771 (0.12%) POCT doubtful : 3/771(ttg IgA?) 1:212

10. POCT + 1 patient 7 years, female Mild FTT Mild failure to gain weight Fatigue Weight: 20.3 kg (25%) Height: 117 cm (25%) BMI: 16 Bristol: 5

11. POCT + 1 patient Hb: 10.1 WBC: 6.000 PLT: 277 AST: 32 ALT: 19

12. POCT + 1 patient History from the father –Birth weight? Feeding pattern? ….. Consanguinity (+) Family history (-) IgA  Normal ttg IgA  >200 U/ml Endoscopy  Duodenal atrophy, scalloping Biopsy  Marsh 3b