1. Leptospirosis in Madagascar Mark Moseley PhD researcher Institute of Biological and Environmental Science University of Aberdeen r01mhm13@abdn.ac.uk

2. Overview 1.What is leptospirosis? 2.Why leptospirosis? 3.Why Madagascar? 4.Project 5.Conclusions

3. 1. What is leptospirosis?

4. 2. Why leptospirosis? Misdiagnosed and underreported

5. 2. Why leptospirosis? Increase in severe forms

6. 2. Why leptospirosis? Socio-economic impacts

7. 2. Why leptospirosis? Linked to poverty Reis et al (2008)

8. 2. Why leptospirosis? Links to biodiversity loss Derne et al 2008

9. 3. Why Madagascar? http://blog.conservation.org/2012/01/to-alleviate-poverty-biodiversity-conservation-is-critical / Biodiversity

10. 3. Why Madagascar? Poverty http://www.oecd.org/dev/emea/40578194.pdf

11. 3. Why Madagascar? High regional incidence ?

12. Project Study design

13. Project Aim To determine the genetic diversity of Leptospira in small mammal hosts in Madagascar at the landscape and national scale Use Leptospira and host diversity data to identify areas at risk of disease emergence

14. Project Results

15. Project Plan

16. Conclusion Karesh et al (2012) Wider significance

17. Thank you Funding Acknowledgements Supervisors : Dr Sandra Telfer Prof Stuart Piertney