1. Intravenous regional anaesthesia Dr. S. Parthasarathy MD., DA., DNB, MD (Acu), Dip. Diab. DCA, Dip. Software statis tics PhD(physiology) Mahatma Gandhi medical college and research institute, puducherry, India

2. History Intravenous regional anaesthesia (IVRA) was first described by August Bier in 1908. He observed that when local anaesthetic was injected IV between two tourniquets on a limb, a rapid onset of anaesthesia in between the tourniquets and a slower onset occurred beyond the distal tourniquet. Not popular until the 1960s when it was reintroduced by Holmes.

3. Original inter cuff IVRA 1 st cuff 2 nd cuff

4. Double tourniquet

5. Indications surgical interventions on the hand, forearm or elbow that will not exceed 1 hour. These include manipulation of forearm fractures, excision of wrist ganglia and palmar fasciotomy. the foot, ankle or lower leg, for example - for removing plates, screws or foreign bodies

6. contraindications To tourniquet sickle cell disease, Raynaud’s disease or scleroderma Allergy to local anaesthetics peripheral vascular disease Surgery needs tourniquet removal during the procedure

7. Advantages Ease of performance Safety Onset Relaxation Controlled duration Rapid recovery Definite -- successful anaesthesia in 96– 100%

8. Disadvantages Use of tourniquet Cannot release tourniquet Exsanguination Toxic reactions Duration ??

9. Technique - equipment Esmarch bandage Tourniquet – single or double ?? Two IV accesses Routine resuscitative equipment Local anaesthetics

10. Preparation Explanation IV access both sides Benzodiazepine premed oral Vein on the dorsum of hand access before tourniquet Exsanguination

11. exsanguination Esmarch bandage or a Rhys-Davis exsanguinator. Crepe bandage elevating the arm for 2–3 minutes while compressing the axillary artery it must be confirmed that no radial pulse is palpable before IV

12. Rhys-Davis exsanguinator.

13. Tourniquet application The double tourniquet (two tourniquets each 6 cm wide) or a single one (14 cm wide) is applied on the arm with generous layers of padding, no wrinkles are formed tourniquet edges do not touch the skin

14. Inflation Proximal touniquet 30 mm above systolic Better to have it as 200 mmHg Legs can go upto 300 mmHg

15. Tourniquet Discomfort Minimum time Release ?? Test deflation and reinflation Resuscitation ready No movement after release

16. double cuff tourniquet If using a double cuff tourniquet, the distal cuff should be deflated. If required for tourniquet pain control, the distal cuff may be inflated, followed by deflation of the proximal cuff. Check for inflation by palpation of the tourniquet cuff.

17. Find LOP and inflate LOP can be defined as the minimum pressure required, at a specific time in a specific tourniquet cuff applied to a specific patient’s limb at a specific location, to stop the flow of arterial blood into the limb distal to the cuff Inflate 100 mm above LOP

18. drugs Prilocaine 0.5 % 40 to 50 ml Lignocaine 0.5 % 40 to 50 ml Ropivacaine, Bupivacaine used Legs upto 70 – 80 ml..dose -- slim?? Preservative free LA Over 90 seconds Chase the LA with NS No adrenaline

19. Anaesthesia is -- Anaesthesia is terribly simple But sometimes It is simply terrible

20. Modified methods Hand Legs Foot Children Dose and size of cuff

22. Complications CNS symptoms 2.1 % to 10 % incidence CVS 15 % ECG changes ?? Minimal drop in BP and HR Dose and preinj. Ischemia Higher levels of local anaesthetic in blood after axillary and lumbar epidural blocks

23. Cross section of nerve fibre Mantle Proximal area Brachial blocks Core = distal or digital- IVRA Mantle Core Vasa nervorum

24. Mechanism Digits first even in intercuff method nerves near the elbow (especially the median and ulnar nerves) are known to be closely accompanied by veins, tributaries of which mainly run through the core of each nerve trunk. nerve trunks are constructed with fibres from the periphery nearest the centre

25. Difference centripetal spread of the anaesthetic effect. Nerve blocks have centrifugal anaesthetic effect because the drug is poured into the nerve from outside

26. IVRA and additives Opioids Relaxants Ketamine Clonidine Neostigmine Paracetamol Ketoroloc

27. IVRA and sympatholytics Guanithidine 10 – 20 mg with 500 units heparin with 20 – 30 ml physiological saline Diagnostic sympathetic block TAO, CRPS etc..

28. Summary Easy simple method 100 % efficacy Very less complications Cheap Adjunct to brachial plexus block ?? But still infamous

29. Helping others is ultimate happiness Thank you all