1. BIO-FREQUENCY SPECTRUM RADIATION & WOUND HEALING
J. M. Schramm, M.A., R. A. Hardesty, M.D., K. C. Oberg, M.D., Ph.D.

2. BFS & WOUND HEALING PROBLEM & BACKGROUND GOALS & OBJECTIVES METHODS
RESULTS
DISCUSSION
CONCLUSIONS

3. CLINICAL PROBLEM Compromised wound healing (bed sores, DM, smokers)
Electromagnetic radiation in wound healing
Microwave radiation in wound healing
Infrared radiation in wound healing
Bio-Frequency Spectrum (BFS) radiation

4. BACKGROUND: BFS & LIGHT SPECTRUM
Light frequency spectrum
Microwave
Infrared
BFS

5. BACKGROUND: BFS RADIATION TREATMENT
Reported results of BFS treatment for bed sores
Reported results from C. Kun, et. al., 1995.

6. GOALS & OBJECTIVES Controlled evaluation of wound healing
MacFarlane flap
tissue survival
Simple incision
breaking strength

7. METHODS: EXPERIMENTAL TECHNIQUES
Anesthesia
Nembutal 2 cc/kg
Flap design
MacFarlane flap
Standardization
4x10 cm template
Stapled incision

8. METHODS: EXPERIMENTAL TECHNIQUES
Anesthesia
Nembutal 2 cc/kg
Incisional design
Midline incision
Standardization
3 cm template
Clipped incision

9. METHODS: TREATMENT PROTOCOL
Control group
No treatment (Social cage 30 min. twice daily)

10. METHODS: TREATMENT PROTOCOL
Treatment groups
Infrared radiation
30 min. twice daily
BFS radiation
30 min. twice daily

11. RESULTS: DATA ANALYSIS
MacFarlane flap
Planimetric analysis
Surface area survivability

12. RESULTS: DATA ANALYSIS
Simple incision
Tensiometer analysis
Wound breaking strength

13. RESULTS: MACFARLANE FLAP
BFS treatment
22.0% (+/- 11.8%)
p<.01 vs. controls
p=.16 vs. IR
IR treatment
30.3% (+/- 10.0%)
Controls
36.9% (+/- 9.6%)

14. RESULTS: SIMPLE INCISION
BFS treatment
2.62N/mm2(+/-0.44N/mm2)
p<.001 vs. controls
p<.10 vs. IR
IR treatment
2.26N/mm2(+/-0.38N/mm2)
p<.03 vs. controls
Controls
1.73N/mm2(+/-0.47N/mm2)

15. DISCUSSION BFS vs. Controls BFS vs. IR Less flap necrosis
Greater wound breaking strength
p<.001
BFS vs. IR
Trend towards less flap necrosis
p=.16

16. CONCLUSIONS BFS as efficient as IR in wound healing BFS trends
Flap necrosis
Simple incision tensile strength
BFS trends
Appears to show greater wound healing than IR
Future research
Verify results
Expand to other models