1. © Copyright 2002 Frost & Sullivan. All Rights Reserved. U.S. Leading Ophthalmic Diseases Markets Untapped Patient Base Holds New Opportunities for Participants “The current estimate of 3.5 million Americans with some form of visual impairment will double by 2030 if measures are not taken to diagnose and treat a range of eye diseases, from age-related macular degeneration to glaucoma. For pharmaceutical companies, this trend offers important opportunities for product development and revenue realization.” Pharmaceuticals Analyst Team Frost & Sullivan

2. © Copyright 2002 Frost & Sullivan. All Rights Reserved. Frost & Sullivan provides: Detailed insights into recent developments and trends Drivers, restraints, challenges, and strategic recommendations Analyst insights into ‘hot topics’ and emerging applications in the leading ophthalmic diseases markets Market sizing and competitive analysis Market forecasts and opportunity analysis Quarterly assessments End-user analysis within each report Key Features

3. © Copyright 2002 Frost & Sullivan. All Rights Reserved. Coverage: The United States Proven methodology encompassing extensive primary and secondary data and research Focused information and strategies that cover business and technology issues Credible data and analysis highlighting industry dynamics Precise strategies to help you create winning business plans What We Offer

4. © Copyright 2002 Frost & Sullivan. All Rights Reserved. Current Market Participants Find out how you compare to with the competition Assess current and future drivers and restraints Determine and exploit new market-share opportunities New Entrants Analyze challenges associated with the industry Calculate time scales for strategy implementation Position yourself to capitalize on the unmet needs of the market Investment Community Analyze long-term strategies of companies Determine participants that will outperform the competition Assess attractiveness of investing in the market Who Will Benefit?

5. © Copyright 2002 Frost & Sullivan. All Rights Reserved. Akorn, Inc. Alcon Laboratories, Inc. Allergan, Inc. Alza Corp. AP Pharma, Inc. Bausch & Lomb, Inc. Boston Life Sciences, Inc. Ciba Vision Corp. Controlled Delivery Systems EyeTech Falcon Ophthalmics, Inc. Genaera Corp. GenVec, Inc. InSite Vision, Inc. Iridex Corp. Ista Pharmaceuticals, Inc. Merck & Co., Inc. Miravant Medical Technologies Novartis Opthalmics, Inc. Oculex Pharmaceuticals, Inc. Pharmacia Corp. QLT, Inc. Santen Pharmaceutical Co. Schein Pharmaceutical, Inc. Key Market Participants

6. © Copyright 2002 Frost & Sullivan. All Rights Reserved. Call toll free 877 G O F ROST (877.463.7876) Fax toll free 888.690.3329 E-mail myfrost@frost.com Visit www.frost.com For More Information