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Genetic Disorders Review
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What is the disorder? Chromosome 11 Inability to manufacture melanin
Often shifting back and forth of eyes ANSWER: ALBINISM
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What is the disorder? Polygenic More common among Asians
Opening in lip and roof of mouth ANSWER: cleft lip/cleft palate
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What is the disorder? Sex-linked trait Lack AHF factor
“bleeder’s disease: ANSWER: hemophilia
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What is the disorder? Chromosome #4
Too many copies of CAG – causes atrophy of the brain Does not manifest itself until 20’s-30’s ANSWER: Huntington’s
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What is the disorder? On X-chromosome Weakening of muscles
Calf muscles enlarge first, usually in young boys ANSWER: Duchenne Muscular Dystrophy
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What is the disorder? Chromosome #15
Accumulation of fat on the brain leads to degeneration of the nervous system Highest in Eastern European Jews ANSWER: Tay Sachs
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What is the disorder? Nondisjunction XXY
Sterile, small testes, breast enlargement in males ANSWER: Klinefelters
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What is the disorder? Nondisjunction Trisomy 21
Mental retardation, round face, extra fold on eyes, sluggish muscles ANSWER: Down Syndrome
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What is the disorder? Chromosome #12
Breakdown of products of phenylalanine Mental retardation if diet does not omit phenylalanine ANSWER: PKU
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What is the disorder? Red blood cells collapse
Carriers are somewhat resistant to malaria Found mostly in African-Americans and people of Mediterranean ANSWER: sickle-cell anemia
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What is the disorder? Nondisjunction Female XO, sterile
Web between neck and shoulders ANSWER: Turner Syndrome
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What is the disorder? Sex-linked trait XcY would be affected male
Inability to detect certain colors ANSWER: color blindness
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What is the disorder? Dominant chromosome #4
Short stature, trident hand, prominent forehead Dwarfism Aa ANSWER: Achrondroplasia
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What is the disorder? Dementia Memory loss, confused
Plaque on the brain ANSWER: Alzheimers
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What is the disorder? Long limbs, enlarged aorta Spidery fingers
Abe Lincoln had it ANSWER: Marfans
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What is the disorder? Polygenic trait
Shunt in brain to drain off fluid Opening of the vertebral column ANSWER: Spina bifida
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What is the disorder? Chromosome #7-salty skin in symptom
Lack enzyme to break down mucous in respiratory and digestive tract Treatment with pounding chest ANSWER: Cystic Fibrosis
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What is this diagram called?
Pedigree Punnett square C.Kayrotype
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What is this diagram called?
Punnett square Pedigree C.Kayrotype ANSWER: C
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What is this diagram called?
Punnett square B. Pedigree C. Karyotype
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What is this diagram called?
Punnett square B. Pedigree C. Karyotype ANSWER: B
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What disorder is this? TURNERS KLINEFELTERS DOWNS METAFEMALE
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What disorder is this? TURNERS KLINEFELTERS DOWNS METAFEMALE
ANSWER: XXY Klinefelters
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What disorder is this? A. TURNERS B. KLINEFELTERS C. METAFEMALE
D. DOWNS
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What disorder is this? A. TURNERS B. KLINEFELTERS C. METAFEMALE
D. DOWNS ANSWER: D
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What are the chances of…
two Achrondroplasia parents having a normal sized child? HINT: AA = dead Aa = achondroplasia aa = normal ANSWER: 25%
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What are the chances… Of a father with hemophilia and a wife of no hemophilia gene having a child with hemophilia? Could any children be carriers? ANSWER: 0% children; girls are carriers
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What disorder is this? A. TURNERS B. KLINEFELTERS C. METAFEMALE
D. DOWNS ANSWER: A
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Which disorders ARE NOT caused by nondisjunction?
Klinefelters Turners Cystic Fibrosis Trisomy 21 Hemophilia ANSWERS: Cystic Fibrosis Hemophilia
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What is the genotypic ratio of the offspring of parents AO and BO?
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What is the genotypic ratio of the offspring of parents AO and BO?
AB BO AO OO B O What is the phenotypic ratio?
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What is the genotypic ratio of the offspring of parents AO and BO?
AB BO AO OO B O What is the phenotypic ratio? 25% each blood types A, B, AB, O
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What type of blood can each of these blood types RECEIVE?
AB+ B- O+, A+ Only O+ Only O- All + O-, B-
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In which phase of mitosis
Are the chromosomes stopped to make a karyotype? A. prophase B. telophase C. metaphase D. anaphase ANSWER: METAPHASE
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How are the chromosomes arranged
In a karyotype? A. smallest to largest B. largest to smallest C. by color D. by shape ANSWER: B
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Who is the oldest child in generation III?
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Who is the oldest child in generation III?
#1
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If red hair is recessive and is shaded in, how many boys and how many girls have red hair?
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If red hair is recessive and is shaded in, how many boys and how many girls have red hair?
2 boys + 2 girls
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Is this person a male or female?
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Is this person a male or female?
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Is this person male or female?
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Is this person male or female?
Normal Or what Disorder?
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Is this person male or female?
Klinefelters
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Is this a male or female?
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Is this a male or female? Female- Normal or a disorder?
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Is this a male or female? Female- TURNERS SYNDROME
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This is a sex-linked trait
This is a sex-linked trait. Why is there no trait (shaded) in Generation II, but can be in III?
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Just carriers in Generation II.
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Which is NOT a sex-linked trait?
Klinefelters Color-Blindness Hemophilia Duchenne Muscular Dystrophy ANSWER: Klinefelters
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Which is NOT genetic disorder?
Color Blindness AIDS Marfans Tay Sachs ANSWER: AIDS
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Make a Punnett Square for two parents AS for sickle-cell anemia.
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Make a Punnett Square for two parents AS for sickle-cell anemia.
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Make a Punnett Square for two parents AS for sickle-cell anemia.
AA (normal RBC) AS (resistant to malaria) SS (sickle-cell disease) A S
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