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Fibrous Dysplasia by Matthew R. DiCaprio, and William F. Enneking J Bone Joint Surg Am Volume 87(8):1848-1864 August 1, 2005 ©2005 by The Journal of Bone.

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Presentation on theme: "Fibrous Dysplasia by Matthew R. DiCaprio, and William F. Enneking J Bone Joint Surg Am Volume 87(8):1848-1864 August 1, 2005 ©2005 by The Journal of Bone."— Presentation transcript:

1 Fibrous Dysplasia by Matthew R. DiCaprio, and William F. Enneking J Bone Joint Surg Am Volume 87(8):1848-1864 August 1, 2005 ©2005 by The Journal of Bone and Joint Surgery, Inc.

2 Clinical photograph demonstrating the irregular “coast-of-Maine” café-au-lait spots on the thorax of a fourteen-year-old girl with McCune-Albright syndrome. Matthew R. DiCaprio, and William F. Enneking J Bone Joint Surg Am 2005;87:1848-1864 ©2005 by The Journal of Bone and Joint Surgery, Inc.

3 Matthew R. DiCaprio, and William F. Enneking J Bone Joint Surg Am 2005;87:1848-1864 ©2005 by The Journal of Bone and Joint Surgery, Inc.

4 Matthew R. DiCaprio, and William F. Enneking J Bone Joint Surg Am 2005;87:1848-1864 ©2005 by The Journal of Bone and Joint Surgery, Inc.

5 Matthew R. DiCaprio, and William F. Enneking J Bone Joint Surg Am 2005;87:1848-1864 ©2005 by The Journal of Bone and Joint Surgery, Inc.

6 Matthew R. DiCaprio, and William F. Enneking J Bone Joint Surg Am 2005;87:1848-1864 ©2005 by The Journal of Bone and Joint Surgery, Inc.

7 Anteroposterior radiograph of the hip of a twenty-two-year-old man who presented with a two- year history of hip pain. Matthew R. DiCaprio, and William F. Enneking J Bone Joint Surg Am 2005;87:1848-1864 ©2005 by The Journal of Bone and Joint Surgery, Inc.

8 Radiographic features of fibrous dysplasia. Matthew R. DiCaprio, and William F. Enneking J Bone Joint Surg Am 2005;87:1848-1864 ©2005 by The Journal of Bone and Joint Surgery, Inc.

9 Axial computed tomography scan demonstrating the “ground-glass” appearance of the lesion within the femoral diaphysis. Matthew R. DiCaprio, and William F. Enneking J Bone Joint Surg Am 2005;87:1848-1864 ©2005 by The Journal of Bone and Joint Surgery, Inc.

10 Sagittal T1-weighted magnetic resonance image of the same lesion, showing primarily a low signal intensity. Matthew R. DiCaprio, and William F. Enneking J Bone Joint Surg Am 2005;87:1848-1864 ©2005 by The Journal of Bone and Joint Surgery, Inc.

11 Histologic features of fibrous dysplasia. Matthew R. DiCaprio, and William F. Enneking J Bone Joint Surg Am 2005;87:1848-1864 ©2005 by The Journal of Bone and Joint Surgery, Inc.

12 The mesenchymal stroma surrounding the dysplastic trabeculae is relatively hypocellular. Matthew R. DiCaprio, and William F. Enneking J Bone Joint Surg Am 2005;87:1848-1864 ©2005 by The Journal of Bone and Joint Surgery, Inc.

13 Higher magnification emphasizes the lack of osteoblast rimming and wide osteoid seams (hematoxylin and eosin, ×400). Matthew R. DiCaprio, and William F. Enneking J Bone Joint Surg Am 2005;87:1848-1864 ©2005 by The Journal of Bone and Joint Surgery, Inc.

14 A field of mature hyaline cartilage is shown adjacent to a bland fibrous stroma (hematoxylin and eosin, ×100). Matthew R. DiCaprio, and William F. Enneking J Bone Joint Surg Am 2005;87:1848-1864 ©2005 by The Journal of Bone and Joint Surgery, Inc.

15 Examples of fibrous dysplasia of the femoral neck treated with fibular grafting. Matthew R. DiCaprio, and William F. Enneking J Bone Joint Surg Am 2005;87:1848-1864 ©2005 by The Journal of Bone and Joint Surgery, Inc.

16 Fifteen-year follow-up radiograph of the proximal part of the femur in a patient treated with a fibular allograft for monostotic fibrous dysplasia. Matthew R. DiCaprio, and William F. Enneking J Bone Joint Surg Am 2005;87:1848-1864 ©2005 by The Journal of Bone and Joint Surgery, Inc.


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