1. Sickle Cell Anemia

2. What Is It? Sickle Cell Anemia is……. A Genetic disease body produces abnormally shaped red blood cells. Red blood cells shaped like crescent/sickle Don’t last as long as red blood cells (lead to anemia ) Can get stuck in blood vessel blocking blood flow Causing pain and organ damage

3.  born with two sickle genes (one from each parent).  only one sickle gene = trait is not expressed because it is recessive.  About 1 in every 12 African American have sickle cell trait(testing can show if trait is present)  Gene responsible for sickle cell anemia is Beta hemoglobin (HBB) / hemoglobin S

5.  Fatigue, Fever, Paleness, Increased Heart Rate, Frequent urination, Excessive thirst, Poor Eye Sight, Skin ulcers, Yellowing of both eyes and skin, Delayed growth, Strokes, Breathlessness, Painful and prolonged erections  Pain  Abdominal  Bone

6.  Taking supplements of Folic Acid  Antibiotics and Vaccines are given to prevent infection  Blood Transfusion  Bone Marrow or Stem Cell transplants  Oxygen loss

8.  Pic 1 –http://www.humanillnesses.com/original/images/hdc_0001_0003_0_img0235.jpg  Pic 2 - http://www.nhlbi.nih.gov/health/dci/images/sickle_cell_01.jpg  Pic 3 - http://www.biologycorner.com/anatomy/blood/sickle_cell_anemia2.jpg  Pic 4 - http://www.empowher.com/files/ebsco/images/si55551319.jpg  Pic 5 - http://nursingcomments.com/wp-content/uploads/2010/03/sickle-cell- anemia.jpg  “Sickle Cell Anemia.” www.nlm.nih.gov. Medicine Plus. Web. 14 April 2011.  Chial, H. (2008) “Rare genetic disorders: Learning about genetic disease through gene mapping, SNPs, and microarray data.” Nature Education 1(1). Web. 14 April 2011.  “What Is Sickle Cell Anemia?” www.nhlbi.nih.gov. U.S. Department of Health & Human Services. Web. 14 Aprill 2011.www.nhlbi.nih.gov  “What Is Sickle Cell Anemia?” www.nhlbi.nih.gov. U.S. Department of Health & Human Services. Web. 14 Aprill 2011.www.nhlbi.nih.gov  “Sickle cell anemia.” www.nlm.nih.gov. Medicine Plus. Web. 13 April 2011.www.nlm.nih.gov