1. NETT Financial & Subcontract Tele-conference Agenda October 11, 2007 Overview of the NETT CCC-hub agreements and formats utilized (PSA vs. FDP) –http://www.theFDP.org/ http://www.theFDP.org/ Funding amounts and budgets for the RAMPART and ALIAS amendments NETT policies re: finances and invoicing –http://sitemaker.umich.edu/nett/files/sop_financial_plan_final01.p dfhttp://sitemaker.umich.edu/nett/files/sop_financial_plan_final01.p df Feedback from group on experience with establishing hub-spoke subcontracts and indirect cost recovery Thoughts on future calls Questions

2. Subcontracts…the “over-arching agreement”over-arching agreement –A hybrid subcontract that can be amended to add protocol activities –Reduces need for multiple, separate subcontracts –Potential for reduction of administrative burden NETT Hub Subcontracts

3. Spoke Color Key for Flow Of Funds Infrastructure awards directly from NINDS Subcontracts with Trial PI Subcontract with NETT CCC Subcontract with Hub ** Source of funding depends on type of agency providing the service Hubs SDMC CCC NINDS Centralized pharmacy or trial services** Trial PI Funds from R01

4. Funding and Budgets - ALIAS Funds flow to the NETT CCC from the University of Miami Current budget includes funds for 1 subject –3 payments for a total of $9100 Contract has been renegotiated to include larger amount Contract will be amended after subjects are enrolled within a Hub Complex

5. Funding and Budgets - RAMPART Funds flow from NETT CCC infrastructure award Initial budgeted funds to be used for pre-IRB approval activities –Public Disclosure and Community Consultation Budgets developed and submitted to NETT CCC after consultation with IRBs Invoices for PD and CC costs provided to NETT CCC Current amount of $50,000 noted in amendment is not the same funds as hub award increase

6. –At the end of each quarter, the CCC will review the study activity of each Hub by reviewing data entry reports provided by the SDMC –The CCC will provide a list of reimbursable activities to the Hub complex –The Hub complex will have ten (10) business days to inform the CCC of any discrepancies with activities included on the CCC list NETT Related Payments to Hubs From the CCC

7. –The CCC will work with the Hub complex to reconcile any discrepancies in a timely manner –The Hub complex will develop an invoice based on a reconciled list of activities –The Hub will forward their invoice to the NETT CCC for processing and payment NETT Related Payments to Hubs From the CCC

8. –The CCC will vendor payments to the Hubs, the Hubs will pay their spokes –Optimizing funding to spoke sites Work with your contracts office to develop hybrid agreements and subcontracts Talk to your research office about adjusting F&A rates for pass through dollars Hub Payments to Spokes

9. Feedback From You NETT CCC – Hub agreements Hub – Spoke agreements IDC recovery –Optimizing funding to spoke sites

10. Thoughts On Future Calls

11. –Review of reconciliation and payment timeframes –Input of NETT investigators and study staff –Regular communication with hub financial and grants personnel List serve address for posing questions (NETT-$-?@umich.edu) Conference calls (as needed) Process Improvement

12. NETT expenditures must comply with the Federal Government Office of Management and Budget Circular A-21, Cost Principles for Educational Institution guidelines http://www.whitehouse.gov/omb/circulars/a021/a02 1.html http://www.whitehouse.gov/omb/circulars/a021/a02 1.html NETT Financial Plan on our website at http://sitemaker.umich.edu/nett/files/sop_financial_ plan_final01.pdf Final Thoughts