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Table 1 The role of microRNAs in cancers microRNAsTumorigenesis miR-9Neuroblastoma miR-10bBreast cancer miR-15, miR-15aLeukemia, pituitary.

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Presentation on theme: "Table 1 The role of microRNAs in cancers microRNAsTumorigenesis miR-9Neuroblastoma miR-10bBreast cancer miR-15, miR-15aLeukemia, pituitary."— Presentation transcript:

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8 Table 1 The role of microRNAs in cancers microRNAsTumorigenesis miR-9Neuroblastoma miR-10bBreast cancer miR-15, miR-15aLeukemia, pituitary adenoma miR-16, miR-16-1Leukemia, pituitary adenoma miR-17-5p, miR-17-92Lung cancer, lymphoma miR-20aLymphoma, lung cancer miR-21Breast cancer, cholangiocarcinoma, head & neck cancer, leukemia, cervical cancer, Pancreatic cancer miR-29, miR-29bLeukemia, cholangiocarcinoma miR-31Colorectal cancer miR-34aPancreatic cancer, Neuroblastoma miR-96Colorectal cancer miR-98Head & neck cancer miR-103Pancreatic cancer miR-107Leukemia, pancreatic cancer miR-125a, miR-125bNeuroblastoma, breast cancer miR-128Glioblastoma miR-133bColorectal cancer miR-135bColorectal cancer miR-143Colon cancer, cervical cancer miR-145Breast cancer, colorectal cancer miR-146Thyroid carcinoma miR-155Breast cancer, leukemia, pancreatic cancer miR-181, miR-181a, miR-181cLeukemia, glioblastoma, thyroid carcinoma miR-183Colorectal cancer miR-184Neuroblastoma miR-196a-2Pancreatic cancer miR-221Glioblastoma, thyroid carcinoma, Pancreatic cancer miR-222Thyroid carcinoma miR-223Leukemia miR-301Pancreatic cancer miR-376Pancreatic cancer let-7, let-7a, let-7a-1, let-7a-3Lung cancer, colon cancer Mol Cancer. 2007; 6: 60. Published online 2007 September 25. doi: 10.1186/1476-4598-6-60. Copyright © 2007 Cho; licensee BioMed Central Ltd.

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12 Let-7g impairs proliferation and enhances cell death. Kumar M S et al. PNAS 2008;105:3903-3908 ©2008 by National Academy of Sciences

13 Kumar M S et al. PNAS 2008;105:3903-3908 ©2008 by National Academy of Sciences

14 Let-7g suppresses tumorigenesis in vivo. Kumar M S et al. PNAS 2008;105:3903-3908 ©2008 by National Academy of Sciences

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16 Janaiah Kota, Raghu R. Chivukula, Kathryn A. O'Donnell, Erik A. Wentzel, Chrystal L. Montgomery, Hun-Way Hwan... Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model Cell, Volume 137, Issue 6, 2009, 1005 - 1017

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