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The ABC of Animal Experiments 2012
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European competence FELASA categories A. Animal technicians A. Animal technicians http://www.felasa.eu/working-groups B. Research technicians B. Research technicians http://la.rsmjournals.com/cgi/reprint/34/3/229 C. Scientists C. Scientists http://la.rsmjournals.com/cgi/reprint/29/2/121 D. Specialists D. Specialists http://la.rsmjournals.com/cgi/reprint/33/1/1 In Finnish In Finnish http://www.uku.fi/jarjestot/FinLAS/
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Category C competence FELASA guidelines Multilateral consultations in Council of Europe (CoE) 1993 80 h Topics UK / Home office European Science Foundation (ESF) ’accredited courses’ ’accredited courses’ www.esf.org www.esf.org www.esf.org
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FELASA Accreditation – quality system for education ‘FELASA Accredited Training’ Maintaining accreditation A & D – 10 years B & C – 5 years Applicant Application & fee Accreditation board Nomination: FELASA board Processes applications YESNOannual (B,C) or biannual (A,D) reports
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Working methods Lectures Analgesia exercise Design group tasks Cost-benefit group task Refereeing exercise Ethics committee application
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Laboratory Animal Science ? Jann Hau: Basic LAS: Concerns the animals themselves Basic LAS: Concerns the animals themselves Applied LAS: Deals with the animal as a scientific model Applied LAS: Deals with the animal as a scientific model
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Laboratory Animal Science ? K-J. Öbrink: Laboratory animal science is a science auxiliary to biological and medical research, but still a well demarcated discipline in research and teaching. Laboratory animal science is a science auxiliary to biological and medical research, but still a well demarcated discipline in research and teaching. It consists of four main parts: It consists of four main parts: genetics and characteristics of laboratory animals effect of homeostatic mechanisms on animal experiments laboratory animal husbandry and basic animal experiment methodology legislation, decrees and laboratory animal ethics
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LAS / Philosophy Long history Aristoteles (384-322 B.C.): Experiment with groups before explanation attempt Aristoteles (384-322 B.C.): Experiment with groups before explanation attempt Galen (130-200 A.D.), Harvey 1657), Boyle (1627-1691), Hunter (1728-1823), Jenner (1749-1823), Darwin (1809-1882), Pasteur (1822-1895), Koch (1843-1910), Banting and Best (1922) Galen (130-200 A.D.), Harvey 1657), Boyle (1627-1691), Hunter (1728-1823), Jenner (1749-1823), Darwin (1809-1882), Pasteur (1822-1895), Koch (1843-1910), Banting and Best (1922) Nobel price in medicine 58 times
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LAS / Philosophy Animals can be used for establishment of hypotheses, but verification requires experiments on humans
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LAS Environment Today Research is in unbelievable pace Expectations of society may be unrealistic Despite increased number of projects, animal numbers per project are decreasing Expectations for work quality of LAS personnel is higher than ever Emphasis on 3Rs The way to cope with this is education
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Animals used in Finland 2010
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Europe 2005
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Rabbit / Council of Europe
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Rabbit pairhousing / CoE
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LAS / Institutions University and research institute facilities Grass root level Grass root level Education and training Education and training Research Research
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LAS Societies FELASA (www.felasa.org ) www.felasa.org GV-SOLAS LASA UK Scand-LASFinLASBaltLASA ESLAV / ECLAM / FALAV EstLASA
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Animal experiments - politics ? Pro research (NSMR, Understanding Animal research, FBR, AMP, www.animalresearchcures.org/ ) Understanding Animal researchFBRAMP www.animalresearchcures.org/Understanding Animal researchFBRAMP www.animalresearchcures.org/ Laboratory Animal Centers Alternative centers (ECVAM, NC3R, CAAT) Welfare (UFAW, FRAME, SEY) Antivivisection (RSPCA, Eurogroup, Animalia) Terrorist (ALF, PETA, EVR, EVRT) PETA
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LAS / Training Complementary courses Competence courses A-D Scientists courses such as this Scientists courses such as this Specialization / D category Specialization / D category University of Copenhagen
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Books Handbook of Laboratory Animal Science, Second Edition: Essential Principles and Practices, Volume I Jann Hau, Gerald L Van Hoosier, Jr. (Eds) CRC Press
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http://netvet.wustl.edu/e-zoo.htm
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