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Published byErnesto Lull Modified over 9 years ago
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Radiation-resistance? There's a Gene for That. New York City Wetware iGEM Team
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Extraordinary Biology Numbers Extremophile Numbers Extraordinary Synthetic Biology Numbers 130 Celsius 130 MPa 1.08-mega-base pair4 Days
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Deinococcus radiodurans (D. rad) One to two hours of acute six to ten Gray radiation exposure. 12,000 Gray!!!!!
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Life of the Cell
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A Bad Day Base DamageSingle Strand BreakDouble Strand Break Active Site Damage
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The Extraordinary Weapon (Kryptonite) 1.H 2 O H· + OH· 2.OH· + OH· H 2 O 2 3.Fe 2+ + H 2 O 2 → Fe 3+ + OH· + OH − Generation of Hydroxyl Radical via the Fenton Reaction
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What Makes D. rad So Special? 1.Cellular Manganese-Iron Ratios 1.Neutralization of Superoxide Radicals 1.Superior DNA Repair Three Basic Approaches
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What Makes D. rad So Special? 1.Cellular Manganese-Iron Ratios Three Basic Approaches
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What Makes D. rad So Special? 2.Neutralization of Superoxide Radicals Three Basic Approaches
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What Makes D. rad So Special? 3.Superior DNA Repair Three Basic Approaches recA Repair Protein
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Making E. coli Radioresistant
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Our Biobricks ruvA ruvB radA tpx ruvA
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Future Applications Bioremediation
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Future Applications Medical Applications
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in vitro meat and moral traditions
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Kosher Vegetarian Vegan
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Legal Precedent: Gelatin
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Legal Precedent: Rennet
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Moral Considerations Ought a vegan or vegetarian to eat meat? Ought a kosher-observer to eat pork? Does cultivating meat without encountering an animal desensitize us as eaters? Does it undermine the relationship between ourselves and animals?
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