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Published byDesirae Haswell Modified over 9 years ago
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SUPERFICIAL FUNGAL INFECTION DERMATOPHYTOSIS THREE GENERA KNOWN TO CAUSE DISEASE -TRICOPHYTON - MICROSPORUM - EPIDERMOPHYTON
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EPIDEMIOLOGY GEOPHILIC - – M.GYPSEUM – M. FERRUGINEUM - T. TERRESTRE - T.VIOLACEUMGEOPHILIC - – M.GYPSEUM – M. FERRUGINEUM - T. TERRESTRE - T.VIOLACEUM ZOOPHILIC - - M. CANIS – CAT, DOGS,SHEEPS - T. EQUINUM – CATS, DOGS,CATTLES - T. VERRUCOSUM – CATS, DOGS, CATTLES,SHEEPSZOOPHILIC - - M. CANIS – CAT, DOGS,SHEEPS - T. EQUINUM – CATS, DOGS,CATTLES - T. VERRUCOSUM – CATS, DOGS, CATTLES,SHEEPS ANTHROPOPHILIC - - E. FLOCCOSUM –M. AUDOUINII –T. MENTAGROPHYTES –T. RUBRUM – T. TONSURANS –ANTHROPOPHILIC - - E. FLOCCOSUM –M. AUDOUINII –T. MENTAGROPHYTES –T. RUBRUM – T. TONSURANS –
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PATHOGENESIS FUNGI MUST OVER COME - EFFECT OF UV LIGHT –TEMPERATURE VARIATION – COMPITION WITH NORMAL FLORA -FUNGISTATIC AGENTS – FATTY ACIDS,SPHINGOSINES - EPIDERMAL GROWTH DTH IMMUNE RESPONSE
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TINEA CAPITIS ECTOTHRIXENDOTHRIX YELLOW- GREEN FLUORESCENCEDULL GRAY-GREEN FLUORESCENCE M.AUDOUINII M.CANIS M.FERRUGINEUM T.SCHOENLEINII NO FLUORESCENCE M.GYPSEUM T.MENTAGROPHYTES T. RUBRUM T.TONSRANS T. VIOLACEUM
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ORGANISMS ASSOCIATED WITH CLINICAL TYPES OF TINEA CAPITIS INFLAMMATORY ZOOPHILIC GEOPHILIC NONINFLAMMATORY ANTHROPOPHLIC ECTOTHRIC BLAK DOT ANTHROPOPHILIC ENDOTHRIX FAVUS M.AUDOUINII M. CANIS M. GYPSEUM T.MENTAGROPHYTE T.TONSURANS T. VERRUCOSUM M.AUDOUINII M. CANIS M.FERRUGINEUM T.TONSURANS T.VIOLACEUM M.GYPSEUM T. SCHOENLEINII T.VIOLACEUM
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TINEA CAPITIS
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BLACK DOT TINEA CAPITIS
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INFLAMMATORY T. CAPITIS
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TINEA BARBAE INFAMATORY TYPE- T. MENTAGROPHTE, T. VERRUCOSUM SUPERFICIAL TYPE - ANTHROPOPHILIC –T. VIOLACEUM,T.RUBRUM CIRCINATE TYPE
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TINEA BARBAE
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TINEA FACEII
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TINEA BARBE
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TYPICAL TINEA CORPORIS
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TINEA CORPORIS
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INFLAMMATORY T. CORPORIS
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TINEA CORPORIS
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TINEA UNGUIUM
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TINEA MANUM
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TINEA CRURIS
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TINEA PEDIS CHRONIC INTERTRIGINOUS TYPE CHRONIC HYPERKERATOTIC TYPE VESICULOBULLOUS TYPE ACUTE ULCERATIVE TYPE
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TINEA PEDIS
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KOH MOUNT
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ENDOTHRIX FUNGUS
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ECTOTHRIX FUNGUS 100X
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TREATMENT SYSTEMIC THERAPY TOPICAL THREAPY **
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SYSTEMIC ANTIFUNGALS ALLYLAMINS – INHIBITS SQUALENE EPOXIDASE BLOCKING BIOSYNTHESIS OF ERGOSTEROL FUNGICIDAL 3 TO 6 mg/kg OD CONTRAINDICATED IN PREGNANCY & LACTATION TRIAZOLES – ITRACONAZOLE, FLUCONAZOLE INHIBIT 14 alfa DEMETHYLASE ENZYME IN CELL MEMBRANE USEFUL FOR CONVERSION OF SQUALENE TO ERGOSTEROL. IMIDAZOLE – KETOCONAZOLE GRISEOFULVIN – DISRUPS MICROTUBULE MITOTIC SPINDLE FORMATON THUS ARREST MITOTIC AT METAPHASE STAGE
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TREATMENT TOPICAL -ALLYLAMINES – TERBINAFINE,NAFTIFINE -BENZYLAMINE - BUTENAFINE -IMIDAZOLES CLOTRIMAZOLE, MICONAZOLE, KETOCONAZOLE -TOLNAFTAE
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THANK YOU….,
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