1. Mutations

2. Definition mutation A mutation is a change in an organism’s DNA – Silent mutations are changes that do not result in a change to the organisms phenotype – Mutations that occur in germ cells (sperm, eggs) are passed on to offspring – Mutations in somatic (body) cells may be harmless, or may result in disease such as cancer

3. Chromosomal Mutations

4. A Point Mutation Resulting in Nonsense

5. A Point Mutation: An Analogy t h e r e d d o g b i t t h e t a n c a t t h e r e d m o g b i t t h e t a n c a t This point mutation changes the meaning, resulting in nonsense

6. A Point Mutation Resulting in Missense

7. A Point Mutation: An Analogy t h e r e d d o g b i t t h e t a n c a t t h e r e d h o g b i t t h e t a n c a t This point mutation changes the meaning, resulting in missense

8. An Insertion Mutation in a Gene

9. An Insertion Mutation: An Analogy t h e r e d d o g b i t t h e t a n c a t t h e r e d r d o g b i t t h e t a n c a This insertion mutation changes the reading frame

10. A Deletion Mutation in a Gene

11. An Deletion Mutation: An Analogy t h e r e d d o g b i t t h e t a n c a t t h e r e d o g b i t t h e t a n c a t _ This deletion mutation changes the reading frame

12. A Frameshift Mutation