1. Lymphatic system

3. Anatomy mathematics Cancer = bad cells = Bad inter cellular junctions = cells slip away Slipping away cells = A PROBLEM. Clearing process = Lymphatics =Veins

16. Anatomy mathematics Lymphatic capillaries = Blind end =endothelium + overlapping junctions + vesicular system +anchoring filaments + Valves

19. Anatomy mathematics Lymph node = Fibrous skeleton( Capsule + trabiculae ) + Reticular stroma Reticulocytes+Rfibers + Lymphoid tissue + Sinuses subcapsular,trabicular and medullary

21. Direction of lymph flow through a lymph node Afferent lymphatic vessel Subcapsular sinus Trabecular or perinodular sinus Medullary sinus Efferent lymphatic vessel Thoracic duct Left subclavian vein General circulation Ross and Pawlina, p. 419

23. capsule subcapsular sinus cortex deep cortex deep cortexmedulla hilus (w/ artery and vein) medullarysinus medullarycord

25. Anatomy mathematics Lymphoid follicle = germinal center + Outer lymphocytes

27. capsule subcapsular sinus cortex reticular cell endothelial cells (easiest to see lining the inner wall, but they line the capsule as well)

31. Anatomy mathematics Lymphoid follicle = Lymphoid nodule

32. germinalcenter lymphoblasts

33. medullarycord medullarysinus macrophage reticular cell lymphocytes

34. medullarysinus medullarycord medullarysinus trabecula (connective tissue)

35. high endothelial venules

56. red pulp centralartery PALS

58. Splenic red pulp Some anatomy mathematics Red pulp = sinusoids + splenic cords Splenic cords = billroth columns

59. Splenic cords and sinuses Ross and Pawlina, p. 427

60. Splenic Circulation Splenic artery Splenic vein PALS: Periarterial (periarteriolar) lymphatic sheath

64. capsule red pulp white pulp trabecula (connective tissue)

77. lumen of crypt stratified squamous epithelium secondary follicles w/ germinal centers

89. cortex medulla

90. cortex (immature T lymphocytes) medulla (mature T lymphocytes) thymic (Hassal’s) corpuscles