1. Past, Present and the Future Rabin Mohanty Consultant Paediatrician Blackpool

2. Before Insulin Before insulin was discovered in 1921, everyone with type 1 diabetes died within weeks to years of its onset JL on 12/15/22 and 2 mos later

3. Impact Of Insulin On Life Expectancy By The 1940’s Age at start of diabetes 503010 Avg. age of death in 1897 58.034.111.3 Avg. age of death in 1945 65.960.545.0 Years Gained82634

4. Manufactured insulin, 'Iletin', United States, 1923

5. Newer insulin pens

6. 1st generation of insulin pumps 1960s

7. Modern Insulin Pump

8. Tandem’s t:slim insulin pump

9. What is an Artificial Pancreas?

10. Islet Cell Transplantation

11. Is Diabetes Curable?  Implantable Insulin Pumps  Islet Cell Transplant  Gene Therapy  Stem Cell  Vaccine  Newer Drugs

12. Blackpool Paediatric Diabetes Service  140 children  4 children on insulin pumps( 2 moved)  4 new children on pumps soon  CGMS monitoring  50% on Basal Bolus  HbA1c falling  Less complications