1. Presented by, Aarti Vaishnav, MS CRIC Director

2. We are a team of 13 full time programmers and about 10 part time students.

3.  USC Norris Cancer Center  USC Cancer Hospital  LAC-USC County Hospital  CHLA  CTSA – USC  Preventive Medicine Dept (Epidemiology and Population Studies)

4. Patient Registry Red CapProtocol CRF Clinical trials Billing systems IRB Systems Membership Data EMR Systems Protocol Management Tools Population Based Studies Publication Management Specimen Management Cancer Center Website QA Committee Shared Resource Support Document Management Grant Data Management DSMB Committee Scientific Committee (CIC) CTRP/Clinical Trials.gov Hospital Registry DB

5.  Manage Servers  Provide PC Support We have moved these tasks to a centralized USC KECK IT Support Team since middle of last year.

7.  CISO serves as a centralized unit to oversee the clinical research infrastructure and assist investigators in their conduct of clinical trials and translational research projects  Staff : 60 +  Investigator Initiated Protocols : 49  Total Open protocols : 170

8.  Support Patient Registry  Data collection for all in house (Investigator Initiated Trials)  Summary Reports  Protocol Tracking and Management  Document Management  Interaction with istar (IRB)  User support

21.  CIC : Clinical Investigation Committee  DSMC : Data Safety Monitoring Committee  QAC : Quality Assurance Committee  Phase I Committee All reports used by these committees are generated by CRIC.

22.  Manage CC Website  Support all other cores (automated ordering, tracking and management)  Manage CC Member data  Manage Publications data  Manage Grants/Proposal data

27. Active CCMember List (Author Name + Keywords + Date Range) Download from PubMed eUtils Web Service Review by CC Members (Email is sent to member for review) Missing publication are added manually Auto Assign Program for each publication based on current membership Batch Upload to the website

35.  Lab/Specimen Management projects  Prevention studies  Disease Specific cohort projects  Support Consortium databases (ex : NANT)  Other Misc projects.

36. We use a in-house developed framework called CAFÉ: Common Application Framework Extensible CAFÉ uses VB.net and SQL server We use SQL Reporting Services for all Reports

37. Integrated Features Audit Trail Access Tracking Role based Security Automated Message System Fully Customizable Remote Login Record Locking Integrated Reports Dash boards Easy Deployment Reusability of forms Automated Data dictionaries

38. Over a 100 Café Projects have been created over the last 5 years to support various types of Research Activities at USC.

39. We are working on making free CAFÉ license available to anyone who wants to use it. License will be available by May 2011. Please contact : Aarti Vaishnav Director, Cancer Research Informatics Core 3234427711 aartiv@usc.edu

40. For additional Information, please visit: http://cafe.usc.edu