1. Figure 1S – Growth phenotypes of IM69 (∆atmA), MV3 (∆npkA), IM69-3 (∆atmA ∆npkA), MRE (mreA::pyr4), IM69-RE (∆atmA mreA::pyr4), APk35 (ankA), IM69-35 (∆atmA ankA), A776 (bimE7), and IM69-228 (∆atmA bimE7). Conidia from these strains were inoculated and percentage of radial growth inhibition was evaluated after growth for 72 hours at 30 o C. The results are the average of four repetitions.

2. 0 20 40 60 80 100 0 1.02.5 5.0 7.5 10.0 0 20 40 60 80 100 0 1.02.5 5.0 7.5 10.0 0 20 40 60 80 100 0 1.02.5 5.0 7.5 10.0 0 20 40 60 80 100 0 1.02.5 5.0 7.5 10.0 Radial Growth (%) HU (mM) Radial Growth (%) A. ∆atmA ∆npkA ∆atmA ∆npkA ∆atmA mreA MRE11 ∆atmA ankA ∆atmA ankA ∆atmA bimE7 ∆atmA bimE7 ∆atmA mreA MRE11 ::pyr4

3. 0 20 40 60 80 100 0 1.02.55.07.5 10.0 MMS (X 10 -3 %) 0 20 40 60 80 100 0 1.02.55.07.5 10.0 MMS (X 10 -3 %) 0 20 40 60 80 100 0 1.02.55.07.5 10.0 MMS (X 10 -3 %) 0 20 40 60 80 100 0 1.02.55.07.5 10.0 MMS (X 10 -3 %) Radial Growth (%) B. ∆atmA ∆npkA ∆atmA ∆npkA ∆atmA ankA ∆atmA ankA ∆atmA bimE7 ∆atmA bimE7 ∆atmA mreA MRE11 ::pyr4 ∆atmA mreA MRE11 ::pyr4

4. 0 20 40 60 80 100 00.0050.010.05 0.1 0.25 4-NQO (  g/ml) 0 20 40 60 80 100 00.0050.010.05 0.1 0.25 4-NQO (  g/ml) 0 20 40 60 80 100 00.0050.010.05 0.1 0.25 4-NQO (  g/ml) 0 20 40 60 80 100 00.0050.010.05 0.1 0.25 4-NQO (  g/ml) Radial Growth (%) C. ∆atmA ∆npkA ∆atmA ∆npkA ∆atmA mreA MRE11 ::pyr4 ∆atmA ankA ∆atmA ankA ∆atmA bimE7 ∆atmA bimE7 ∆atmA mreA MRE11 ::pyr4

5. 0 20 40 60 80 100 0 5 10 25 50 75 CPT (  M) Radial Growth (%) D. ∆atmA ∆npkA ∆atmA ∆npkA ∆atmA ankA ∆atmA ankA 0 20 40 60 80 100 0 5 10 25 50 75 CPT (  M) Radial Growth (%) 0 20 40 60 80 100 0 5 10 25 50 75 CPT (  M) Radial Growth (%) ∆atmA bimE7 ∆atmA bimE7 0 20 40 60 80 100 0 5 10 25 50 75 CPT (  M) Radial Growth (%) ∆atmA mreA MRE11 ::pyr4 ∆atmA mreA MRE11 ::pyr4