1. LIVE INTERACTIVE LEARNING @ YOUR DESKTOP Tuesday, February 20, 2007 7:00 p.m. to 8:00 p.m. Eastern time NSDL/NSTA Web Seminar: Small Creatures Under the Microscope— The Exploratorium

2. http://nsdl.org Access to real research and experts Video and digital images to visually enhance your teaching Dynamic, microscopic views of life under the lens http://nsdl.org http://exploratorium.edu

3. Small Creatures Under the Microscope - the Exploratorium http://nsdl.org

4. Today’s Presenters Dr. Kristina Yu Dr. Sherry Hsi Dr. Karen Kalumuck

5. Microscope Imaging Station at the Exploratorium http://nsdl.org

6. The MIS Website - a digital resource for microscopic images 1. Features of the MIS website: an overview of contents & types of images 2. About our topics - 3 examples: zebrafish, sea urchins & stem cells 3. Using images to stimulate inquiry: an example http://nsdl.org

7. Do you have access to good-quality compound microscopes? Stamp your answer. Elementary & Middle School?High School & Above? Yes No Yes No http://nsdl.org

8. Let’s do a poll question! How many students share a microscope when using them in your classroom? a) Zero b) 1 student per microscope c) 2-4 students per microscope d) More than 4 students per microscope http://nsdl.org

9. www.exploratorium.edu/imaging_station (insert screenshot of homepage here)

10. www.exploratorium.edu/imaging_station Features: Articles about researchers & their work, multimedia related to the story Gallery : A collection of still images and movies highlighting organisms and cells used in biomedical research. Activities: Conversation provoking, image- based activities and Teacher Institute tested activities to be added soon! http://nsdl.org

11. It’s Time to Play: Name That Cell! 123 1. 2. 3. http://nsdl.org

12. www.exploratorium.edu/imaging_station Images & movies available in the gallery http://nsdl.org

13. Which of these is the wildtype? Stamp your answer

14. How often do you use images from the web in your classroom? Elementary & Middle SchoolHigh School & Above (0 = never, 5 = occasionally, 10 = the Web is my primary source) Type your answer in the box

15. Zebrafish (Danio rerio) Commonly found in freshwater aquariums Widely used in basic & biomedical research Clear eggs are good for studying developmental processes Adult fish produce dozens of eggs at a time

16. Zebrafish development: How long do you think this process takes? Write Your Guesses on the Chat http://nsdl.org

17. Zebrafish are used to study cardiovascular diseases Mutant heart Normal heart Normal heart with green fluorescent protein http://nsdl.org *Note: You will need to download the free version of Quick Time to view these movies.

18. Sea urchins Lytechinus pictus Clear eggs Can collect sperm & eggs separately to time fertilization Embryos will develop synchronously

19. Sea urchin development http://nsdl.org

20. stem cells Pluripotent mouse stem cells Cardiac myocytes derived from mouse stem cells Neural cells derived from mouse stem cells (Mouse embryonic) http://nsdl.org *Note: You will need to download the free version of Quick Time to view this movie.

21. Images for Inquiry Human white blood cells Xenopus embryos Sea urchin embryo Amoeba Mouse embryonic stem cells Human cheek cells Elodea cells Human red blood cells Zebrafish embryo Which images are of differentiated cells, that is, specialized for a specific function? What are their functions?

22. Images for Inquiry Human white blood cells Xenopus embryosSea urchin embryo Amoeba Mouse embryonic Stem cells Human cheek cellsElodea cellsHuman red blood cells Zebrafish embryo Which images show cells that are not differentiated? Do you think they will continue to develop and specialize? What might they become?

23. Neural connectivity in Zebrafish Cancer & the link to stem cells Cell cycle and mitosis Planaria as a model for regenerative medicine Xenopus (African clawed frog) as a model for vertebrate development More topics coming soon!

24. www.exploratorium.edu/library http://nsdl.org

26. Go to http://nsdl.org and click on the K-12 audience pagehttp://nsdl.org Download this seminar’s companion guide with resources from the seminar and more Expert Voices blog with Charlie Carlson, Exploratorium’s Director of Life Sciences http://expertvoices.nsdl.org http://nsdl.org

27. http://nsdl.org THANK YOU! http://exploratorium.edu Dr. Kristina Yu Kristina@exploratorium.edu Dr. Karen Kalumuck Karenk@exploratorium.edu Dr. Sherry Hsi Sherryh@exploratorium.edu

28. National Science Teachers Association Gerry Wheeler, Executive Director Frank Owens, Associate Executive Director Conferences and Programs Al Byers, Assistant Executive Director e-Learning LIVE INTERACTIVE LEARNING @ YOUR DESKTOP NSTA Web Seminars Flavio Mendez, Program Manager Jeff Layman, Technical Coordinator Susan Hurstcalderone, Volunteer Chat Moderator