1. 4 A Tour of the Cell Brad Stith, University of Colorado Denver4
A Tour of the Cell
Questions prepared by
Brad Stith, University of Colorado Denver
Jung Choi, Georgia Institute of Technology

2. Which cellular structure is common to all three domains of life?
nucleus
endoplasmic reticulum
mitochondria
phospholipid bilayer cell membrane
endocytotic vesicles
Answer: D

3. Which cellular structure is common to all three domains of life?
nucleus
endoplasmic reticulum
mitochondria
phospholipid bilayer cell membrane
endocytotic vesicles 3

4. endoplasmic reticulum nucleus lysosomes Golgi plasma membrane
Enzymes responsible for biosynthesis of membrane lipids would be located in what part of the cell?
endoplasmic reticulum
nucleus
lysosomes
Golgi
plasma membrane
Answer: A
This question focuses on Concept 4.4. 4

5. endoplasmic reticulum nucleus lysosomes Golgi plasma membrane
Enzymes responsible for biosynthesis of membrane lipids would be located in what part of the cell?
endoplasmic reticulum
nucleus
lysosomes
Golgi
plasma membrane 5

6. Mitochondria and chloroplasts have double membranes.
Which of the following is not an argument for the theory that mitochondria and chloroplasts evolved from prokaryotic endosymbionts?
Mitochondria and chloroplasts have double membranes.
Mitochondria and chloroplasts have their own ribosomes.
Mitochondria and chloroplasts have their own DNA.
The mitochondrial and chloroplast genomes are circular.
All of the above support the endosymbiotic theory.
Answer: E
This question focuses on Concept 4.5. 6

7. Mitochondria and chloroplasts have double membranes.
Which of the following is not an argument for the theory that mitochondria and chloroplasts evolved from prokaryotic endosymbionts?
Mitochondria and chloroplasts have double membranes.
Mitochondria and chloroplasts have their own ribosomes.
Mitochondria and chloroplasts have their own DNA.
The mitochondrial and chloroplast genomes are circular.
All of the above support the endosymbiotic theory. 7

8. Autophagy removes old damaged organelles like mitochondria
Autophagy removes old damaged organelles like mitochondria. Decreased autophagy results in degeneration and inflammation and may result in the “symptoms” of aging. Which of the following organelle(s) is/are central to autophagy?
smooth ER
peroxisomes
rough ER
lysosomes
Golgi apparatus
Answer: D
This question covers a hot area of research and involves application of information on lysosomes. 8

9. Autophagy removes old damaged organelles like mitochondria
Autophagy removes old damaged organelles like mitochondria. Decreased autophagy results in degeneration and inflammation and may result in the “symptoms” of aging. Which of the following organelle(s) is/are central to autophagy?
smooth ER
peroxisomes
rough ER
lysosomes
Golgi apparatus 9

10. What is the correct order of the exocytosis or secretion pathway?
rough ER, endosome, Golgi, smooth ER
rough ER, Golgi, smooth ER, exocytosis
smooth ER, rough ER, exocytosis, Golgi
rough ER, Golgi, transport vesicle, exocytosis
rough ER, Golgi, endosome, exocytosis, transport vesicle
Answer: D 10

11. What is the correct order of the exocytosis or secretion pathway?
rough ER, endosome, Golgi, smooth ER
rough ER, Golgi, smooth ER, exocytosis
smooth ER, rough ER, exocytosis, Golgi
rough ER, Golgi, transport vesicle, exocytosis
rough ER, Golgi, endosome, exocytosis, transport vesicle 11

12. lysosomes, transport vesicles, plasma membrane
Brefeldin A is a drug that disrupts transport from the ER to the Golgi apparatus. What other organelles and membranes are affected?
lysosomes, transport vesicles, plasma membrane
mitochondria, peroxisomes, plasma membrane
vacuoles, mitochondria, plasma membrane
lysosomes, transport vesicles, nuclear membrane
all intracellular organelles and membranes
Answer: A
This question corresponds with Concept 4.4. It addresses student understanding of membrane flow and the continuity of the endomembrane system. 12

13. lysosomes, transport vesicles, plasma membrane
Brefeldin A is a drug that disrupts transport from the ER to the Golgi apparatus. What other organelles and membranes are affected?
lysosomes, transport vesicles, plasma membrane
mitochondria, peroxisomes, plasma membrane
vacuoles, mitochondria, plasma membrane
lysosomes, transport vesicles, nuclear membrane
all intracellular organelles and membranes 13