1. Chapter 13 – Blood Chapter 22 – Fetal Circulation Chapter 22 pages 458 - 459

2. Blood Blood is made up of two parts 1.Formed Elements Red blood cells White blood cells Platelets 2.Plasma

3. Formed Elements Red Blood Cells – Also called erythrocytes – No nucleus – Made in the Marrow of Bones (the middle of bones) – Contains the protein Hemoglobin. This allows the cell to carry oxygen. – If arterial blood is carrying low amounts of oxygen then the kidney produces a hormone called erythropoietin. This tells the body to produce more red blood cells

4. Red Blood Cells Double Concave No nucleus Protein Hemoglobin Made in Bone Marrow

5. White Blood Cells Called Leukocytes Many different types of white blood cells Made in the marrow of bones Use a combination of special proteins, enzymes, and phagocytosis to kill infections

7. Platelets Also called Thrombocytes Made in the Marrow of bones Involved with blood clotting No Nucleus

8. Platelet No Nucleus Smaller than RBC Forms Blood Clots

11. Where do blood cells come from There are a type of stem cell found in the marrow of bones These stem cells can create any type of blood cell including – Platelets – Red Blood cells – All types of White blood cells Page 251

13. Plasma Mostly made up of water Transports dissolved gases  CO 2, O 2 Transports nutrients  Amino acids, glucose Transports wastes  Urea, Uric Acid Transports hormones  Insulin, epinephrine Has Plasma Proteins – Fibrinogen, prothrombin  These proteins help create blood clots

14. Capillary Exchange On the arterial end of capillaries the blood pressure pushing into cells is greater than the osmotic pressure pushing out of cells. – The result is that materials move into cells On the Venous end of capillaries the blood pressure pushing into cells is lesser than the osmotic pressure pushing out of cells. – The result is that materials move out of cells

17. Review Page 260 -261 Testing yourself – Questions 1- 12

18. Blood Circulation in a Fetus A fetus does not use its lungs for gas exchange – Instead it relies on the mother for gas exchange The fetus has a whole in the heart that connects the right atrium to the left atrium called the oval opening – Most of the blood coming into the right atrium goes to the left atrium Any blood that goes into the Right Ventricle goes up through the pulmonary trunk and is diverted and enters the aorta via the arterial duct

20. The Fetus does its gas and nutrient exchange through the placenta. Oxygenated blood going to the fetus heart goes through the umbilical vein The umbilical vein enters the liver and then joins with the venous duct, which then enters the heart via the inferior vena cava When blood leaves the heart it goes to the body and deoxygenated blood goes back to the placenta through the umbilical artery