1. gefitinib EGFR inhibitor Non-small cell lung cancer Rash & diarrhea

2. erlotinib EGFR inhibitor non-small cell lung cancer & pancreatic carcinoma (better than gefitinib) Rash& diarrhea

3. Cetuximab EGFR antibody Colorectal cancer & head and neck cancer Rash & diarrhea

4. trastuzumab (aka herceptin) EGFR antibody Breast cancer or metastatic gastric cancer w/HER2 expression cardiotoxicity

5. imatinib Inhibitor of BCR-ABL, C-KIT, and PDGFR CML, GI stromal tumor expressing KIT, idiopathic hypereosinophilic syndrome

6. Sorafenib Inhibitor of B-RAF Renal cell carcinoma & hepatocellular carcinoma

7. Rapamycin (sirolimus) mTOR inhibitor Rejection prophylaxis for renal transplant

8. Bortezomib Inhibits 20S subunit of proteasome Multiple myeloma & mantle cell lymphoma

9. Bevacizumab VEGF/VEGFR antibody Metastatic colorectal cancer & NSCLC Contraindicated for cerebrally metastasized NSCLC

10. sunitinib VEGF/VEGFR inhibitor Renal cell carcinoma & GI stromal tumor

11. thalidomide Inhibits TNF-a and bFGF Multiple myeloma & erythema nodosum leprosum Beware thrombosis

12. lenalidomide Inhibits TNF-a and bFGF (better than thal.) Multiple myeloma & myelodysplastic syndrome Lesser risk of thrombosis than thalidomide

13. rituximab CD-20 antibody B cell non-hodgkin lymphoma Beware immunosuppression