1. Figure 26.8 The Filtration Membrane Process Diagrams Step-by-Step Copyright © 2007 by John Wiley & Sons, Inc.

2. Filtration slitPedicel of podocyte Fenestration (pore) of glomerular endothelial cell Basal lamina Lumen of glomerulus (b) Filtration membrane TEM 78,000x (a) Details of filtration membrane Filtration slit Pedicel Fenestration (pore) of glomerular endothelial cell: prevents filtration of blood cells but allows all components of blood plasma to pass through Podocyte of visceral layer of glomerular (Bowman’s) capsule 1

3. Filtration slitPedicel of podocyte Fenestration (pore) of glomerular endothelial cell Basal lamina Lumen of glomerulus (b) Filtration membrane TEM 78,000x (a) Details of filtration membrane Filtration slit Pedicel Fenestration (pore) of glomerular endothelial cell: prevents filtration of blood cells but allows all components of blood plasma to pass through Basal lamina of glomerulus: prevents filtration of larger proteins Podocyte of visceral layer of glomerular (Bowman’s) capsule 1 2

4. Filtration slitPedicel of podocyte Fenestration (pore) of glomerular endothelial cell Basal lamina Lumen of glomerulus (b) Filtration membrane TEM 78,000x (a) Details of filtration membrane Filtration slit Pedicel Fenestration (pore) of glomerular endothelial cell: prevents filtration of blood cells but allows all components of blood plasma to pass through Basal lamina of glomerulus: prevents filtration of larger proteins Slit membrane between pedicels: prevents filtration of medium-sized proteins Podocyte of visceral layer of glomerular (Bowman’s) capsule 1 2 3